Classify patients with Moyamoya disease according to their cognitive performance might be helpful in clinical and practical with support vector machine based on hypergraph

Wang, Ying; Zhang, Nan; Qian, Sheng; Liu, Jian; Yu, Shaojie; Li, Nan; Xia, Chengyu

doi:10.1002/hbm.26218

Cited by 3 publications

(2 citation statements)

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“…These findings are consistent with those of a study conducted by Sun and colleagues, which showed that 31.5% (29 out of 92) of patients experienced cognitive dysfunctions (Sun et al, 2022). These behavioral dysfunctions are intricately linked to specific neural circuits or brain networks that support complex emotional and cognitive abilities, as well as a sophisticated interplay between them (Wang et al, 2023;Lei et al, 2020).…”

Section: Introductionsupporting

confidence: 91%

Profile of speech and cognitive impairments in a patient with moyamoya disease: a longitudinal case study

Pashkov,

Filimonova,

Martirosyan

et al. 2023

Preprint

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Moyamoya is a rare chronic brain vascular disease with a set of potential life-threatening consequences due to a high probability of stroke occurrence. Patients suffering from this disease are often presented with diverse and severe sensory, motor and cognitive deficits, which often lead to general inability to work and, in the most severe cases, to complete loss of self-serving skills and gross disturbance of vital homeostatic functions. Here we present a case of a patient with moyamoya disease, who has been dynamically observed over more than 4 years after the first manifestation of her symptoms. We have been tracking the appearance of patient’s new symptoms and resolution of existing ones after neurosurgical treatment (revascularization surgery) with in-depth neurological examination, neuropsychological assessment and fMRI/DTI sessions. This study represents one of the first attempts to rigorously estimate the patterns of deficits at different levels, connecting neural circuits affected by the disease to behavior. Our findings lend further support to the idea that revascularization surgery can improve cognitive performance and highlights the importance of long-term follow-up in understanding the effects of surgery on brain function.

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Section: Introductionsupporting

confidence: 91%

Profile of speech and cognitive impairments in a patient with moyamoya disease: a longitudinal case study

Pashkov,

Filimonova,

Martirosyan

et al. 2023

Preprint

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show abstract

“…We included 12 other studies that were not case reports nor case series (44)(45)(46)(47)(48)(49)(50)(51)(52)(53)(54)(55). These comprised in total 1043 MMD patients (mean age: 37 years old; mean percentage of females: 58%).…”

Section: Results Of Other Studies On Psychiatric Symptoms In Moyamoya...mentioning

confidence: 99%

Psychiatric manifestations in moyamoya disease: more than a puff of smoke? a systematic review and a case-reports meta-analysis

Saccaro,

Mallet,

Wullschleger

et al. 2024

Front. Psychiatry

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IntroductionMoyamoya disease (MMD) is a life-threatening condition characterized by stenosis of intracranial arteries. Despite the frequency and the impact of psychiatric symptoms on the long-term prognosis and quality of life of MMD patients, no systematic review on this topic exists.MethodsThis systematic review and meta-analysis included 41 studies (29 being case reports), from PubMed, Scopus, Embase until 27/3/2023, on MMD patients exhibiting psychiatric symptoms.ResultsDespite a fair average quality of the articles, quantitative synthesis through logistic regression was possible only for case reports, due to heterogeneity between the other studies. Psychosis, the most frequent psychiatric symptom reported in case reports, was more frequent in MMD patients with left hemisphere involvement. Neurological symptoms occurrence increased the odds of MMD diagnosis preceding psychiatric symptoms. Psychiatric symptoms are highly prevalent in MMD patients and are relatively often the only presenting symptoms.DiscussionWe discuss the diagnostic, therapeutic, and prognostic implications of recognizing and characterizing specific psychiatric symptoms in MMD, outlining preliminary guidelines for targeted pharmacological and psychotherapeutic interventions. Lastly, we outline future research and clinical perspectives, striving to enhance the oft-overlooked psychiatric care for MMD patients and to ameliorate their long-term outcome.Systematic Review Registrationhttps://www.crd.york.ac.uk/PROSPERO/, identifier CRD42023406303.

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Classify patients with Moyamoya disease according to their cognitive performance might be helpful in clinical and practical with support vector machine based on hypergraph

Wang

Zhang

Qian

et al. 2023

Human Brain Mapping

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Moyamoya disease (MMD) patients were now classified according to their cerebrovascular manifestations, with cognition and emotion ignored, which attenuated the therapy. The present study tried to classify them based on their cognitive and emotional performance and explored the neural basis underlying this classification using resting‐state fMRI (rs‐fMRI). Thirty‐nine MMD patients were recruited, assessed mental function and MRI scanned. We adopted hierarchical analysis of their mental performance for new subtypes. Next, a three‐step analysis, with each step consisting of 10 random cross validation, was conducted for robust brain regions in classifying the three subtypes of patients in a support vector machine (SVM) model with hypergraph of rs‐fMRI. We found three new subtypes including high depression‐high anxiety‐low cognition (HE‐LC, 50%), low depression‐low anxiety‐high cognition (LE‐HC, 14%), and low depression‐low anxiety‐low cognition (LE‐LC, 36%), and no hemorrhagic MMD patients fell into the LE‐HC group. The temporal and the bilateral superior frontal cortex, and so forth were included in all 10 randomized SVM modeling. The classification accuracy of the final three‐way classification model was 67.5% in average of 10 random cross validation. In addition, the S value between the frontal cortex and the angular cortex was positively correlated with the anxiety score and backward digit span ( p < .05). Our results might provide a new perspective for MMD classification concerning patients' mental status, guide timely surgery and suggest angular cortex, and so forth should be protected in surgery for cognitive consideration.

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Classify patients with Moyamoya disease according to their cognitive performance might be helpful in clinical and practical with support vector machine based on hypergraph

Cited by 3 publications

References 35 publications

Profile of speech and cognitive impairments in a patient with moyamoya disease: a longitudinal case study

Profile of speech and cognitive impairments in a patient with moyamoya disease: a longitudinal case study

Psychiatric manifestations in moyamoya disease: more than a puff of smoke? a systematic review and a case-reports meta-analysis

Classify patients with Moyamoya disease according to their cognitive performance might be helpful in clinical and practical with support vector machine based on hypergraph

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