Archives of Otolaryngology - Head and Neck Surgery
 1985
DOI: 10.1001/archotol.1985.00800110073005
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Circulating Immunocomplexes and Laryngeal Carcinoma

Angela Denaro1,
Rosa Caruso2,
Marco Rossi3
et al.
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Cited by 10 publications

(3 citation statements)
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“…Pored op{teg imunosupresi-vnog imunosupresivnog dejstva, interakcije malignog tkiva i imunolo{kog sistema imaju jo{ jedan va'an nivo, a {to je specifi~ni imunolo{ki odgovor na tumor asocirane antigene (TAA) 7,8,9 . U vezi s tim odgovorom se u odredjenoj fazi maligne bolesti pojavljuju i specifi~ni blokiraju}i serumski faktori, u po~etnoj fazi bolesti su to necitotoksi~na antitela, u srednjoj solubilni imuni kompleksi, a u kasnijim fazama bolesti imunokompleksi i solubilni antigeni.…”
unclassified
“…U vezi s tim odgovorom se u odredjenoj fazi maligne bolesti pojavljuju i specifi~ni blokiraju}i serumski faktori, u po~etnoj fazi bolesti su to necitotoksi~na antitela, u srednjoj solubilni imuni kompleksi, a u kasnijim fazama bolesti imunokompleksi i solubilni antigeni. Sve tri komponente bloki-raju}ih serumskih faktora doprinose da maligne }elije izbegnu imunolo{ku destrukciju, stoga bi njihovo odredjivanje moglo da ima zna~aja za dijagnozu i prognozu malignih bolesti 8,9 . Rezultati istra'ivanja imunih kompleksa u serumu bolesnika sa malignim tumorima potvrdili su ovu pretpostavku.…”
unclassified
“…Solubilni cirkuli{u}i imuni kompleksi prate razvoj mnogih malignih bolesti i njima se pripisuje blokiraju}a, selektivna imunosupresivna aktivnost za specifi~nu antitumorsku imunonst. S toga se smatra da oni imaju veliki zna~aj u mehanizmima kojim maligno tkivo izmi~e imunolo{koj destrukciji pa prema tome imaju i zna~ajnu prognosti~ku vrednost 8,9,10 . Pove}ane koncentracije serumskih IgG i IgA posle hi-rur{kog uklanjanja malignog tkiva govore da ovi imuno-lo{ki poreme}aji nisu izazvani malignim tumorom, ve} verovatno nekim drugim prate}im i/ili prethodnim uzro~nikom.…”
Section: Diskusijaunclassified
See 2 more Smart Citations
Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task.
“…Pored op{teg imunosupresi-vnog imunosupresivnog dejstva, interakcije malignog tkiva i imunolo{kog sistema imaju jo{ jedan va'an nivo, a {to je specifi~ni imunolo{ki odgovor na tumor asocirane antigene (TAA) 7,8,9 . U vezi s tim odgovorom se u odredjenoj fazi maligne bolesti pojavljuju i specifi~ni blokiraju}i serumski faktori, u po~etnoj fazi bolesti su to necitotoksi~na antitela, u srednjoj solubilni imuni kompleksi, a u kasnijim fazama bolesti imunokompleksi i solubilni antigeni.…”
unclassified
“…U vezi s tim odgovorom se u odredjenoj fazi maligne bolesti pojavljuju i specifi~ni blokiraju}i serumski faktori, u po~etnoj fazi bolesti su to necitotoksi~na antitela, u srednjoj solubilni imuni kompleksi, a u kasnijim fazama bolesti imunokompleksi i solubilni antigeni. Sve tri komponente bloki-raju}ih serumskih faktora doprinose da maligne }elije izbegnu imunolo{ku destrukciju, stoga bi njihovo odredjivanje moglo da ima zna~aja za dijagnozu i prognozu malignih bolesti 8,9 . Rezultati istra'ivanja imunih kompleksa u serumu bolesnika sa malignim tumorima potvrdili su ovu pretpostavku.…”
unclassified
“…Solubilni cirkuli{u}i imuni kompleksi prate razvoj mnogih malignih bolesti i njima se pripisuje blokiraju}a, selektivna imunosupresivna aktivnost za specifi~nu antitumorsku imunonst. S toga se smatra da oni imaju veliki zna~aj u mehanizmima kojim maligno tkivo izmi~e imunolo{koj destrukciji pa prema tome imaju i zna~ajnu prognosti~ku vrednost 8,9,10 . Pove}ane koncentracije serumskih IgG i IgA posle hi-rur{kog uklanjanja malignog tkiva govore da ovi imuno-lo{ki poreme}aji nisu izazvani malignim tumorom, ve} verovatno nekim drugim prate}im i/ili prethodnim uzro~nikom.…”
Section: Diskusijaunclassified
See 1 more Smart Citation
Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task.
Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task.
Exaggerated anticipatory anxiety is common in social anxiety disorder (SAD). Neuroimaging studies have revealed altered neural activity in response to social stimuli in SAD, but fewer studies have examined neural activity during anticipation of feared social stimuli in SAD. The current study examined the time course and magnitude of activity in threat processing brain regions during speech anticipation in socially anxious individuals and healthy controls (HC). Method Participants (SAD n = 58; HC n = 16) underwent functional magnetic resonance imaging (fMRI) during which they completed a 90s control anticipation task and 90s speech anticipation task.
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