Cimetidine Therapy for Recalcitrant Warts in Adults

Treatment of viral warts with cimetidine: an open-label study

“…Although this was an open study, the success rate is considerably greater than that expected for spontaneous resolution during the treatment period and compares favourably with those quoted for cryosurgery, cautery, keratolytics or pulsed dye laser and previous cimetidine studies 3–6,8 . Our patients generally tolerated cimetidine well and the majority improved with treatment.…”

Treatment of viral warts with cimetidine: an open-label study

“…Although this was an open study, the success rate is considerably greater than that expected for spontaneous resolution during the treatment period and compares favourably with those quoted for cryosurgery, cautery, keratolytics or pulsed dye laser and previous cimetidine studies 3–6,8 . Our patients generally tolerated cimetidine well and the majority improved with treatment.…”

What's New in the Treatment of Viral Warts in Children

“…These authors state that they continue to use cimetidine as a first‐line therapy for multiple recalcitrant warts in children but not in adults, since cimetidine appeared not to be useful in patients older than 17 years of age. Similar good results were obtained by Glass and Solomon (58), who advocate higher doses of cimetidine (35–40 mg/kg/day) to achieve a complete response. An open study of 41 patients showed a complete resolution of multiple warts in 14 of 16 children and 11 of 25 adults with oral cimetidine 30–40 mg/kg/day (59); no side effects were noted in children, but were common in adults.…”

Duct Tape for the Treatment of Common Warts in Adults

“…In the pediatric population, it has been estimated that up to 65% of warts resolve spontaneously within 2 years, 15 whereas some researchers believe that spontaneous resolution of warts occurs rarely in adults. 16 A similar inverse relationship between age of subjects and response rates to wart treatment has been documented in the literature by Horn et al 17 in a 3-arm study that assessed the efficacy of antigen injection vs interferon injection vs control (isotonic sodium chloride solution) for the treatment of warts. In that study, the nonresponders tended to be older than the responders, and further analysis showed that age younger than 40 years was positively associated with probability of a response.…”

Treatment of viral warts with cimetidine: an open-label study

“…Although this was an open study, the success rate is considerably greater than that expected for spontaneous resolution during the treatment period and compares favourably with those quoted for cryosurgery, cautery, keratolytics or pulsed dye laser and previous cimetidine studies 3–6,8 . Our patients generally tolerated cimetidine well and the majority improved with treatment.…”

What's New in the Treatment of Viral Warts in Children

“…These authors state that they continue to use cimetidine as a first‐line therapy for multiple recalcitrant warts in children but not in adults, since cimetidine appeared not to be useful in patients older than 17 years of age. Similar good results were obtained by Glass and Solomon (58), who advocate higher doses of cimetidine (35–40 mg/kg/day) to achieve a complete response. An open study of 41 patients showed a complete resolution of multiple warts in 14 of 16 children and 11 of 25 adults with oral cimetidine 30–40 mg/kg/day (59); no side effects were noted in children, but were common in adults.…”

Duct Tape for the Treatment of Common Warts in Adults

“…In the pediatric population, it has been estimated that up to 65% of warts resolve spontaneously within 2 years, 15 whereas some researchers believe that spontaneous resolution of warts occurs rarely in adults. 16 A similar inverse relationship between age of subjects and response rates to wart treatment has been documented in the literature by Horn et al 17 in a 3-arm study that assessed the efficacy of antigen injection vs interferon injection vs control (isotonic sodium chloride solution) for the treatment of warts. In that study, the nonresponders tended to be older than the responders, and further analysis showed that age younger than 40 years was positively associated with probability of a response.…”

Treatment of viral warts with cimetidine: an open-label study

“…Although this was an open study, the success rate is considerably greater than that expected for spontaneous resolution during the treatment period and compares favourably with those quoted for cryosurgery, cautery, keratolytics or pulsed dye laser and previous cimetidine studies 3–6,8 . Our patients generally tolerated cimetidine well and the majority improved with treatment.…”

What's New in the Treatment of Viral Warts in Children

“…These authors state that they continue to use cimetidine as a first‐line therapy for multiple recalcitrant warts in children but not in adults, since cimetidine appeared not to be useful in patients older than 17 years of age. Similar good results were obtained by Glass and Solomon (58), who advocate higher doses of cimetidine (35–40 mg/kg/day) to achieve a complete response. An open study of 41 patients showed a complete resolution of multiple warts in 14 of 16 children and 11 of 25 adults with oral cimetidine 30–40 mg/kg/day (59); no side effects were noted in children, but were common in adults.…”

Duct Tape for the Treatment of Common Warts in Adults

“…In the pediatric population, it has been estimated that up to 65% of warts resolve spontaneously within 2 years, 15 whereas some researchers believe that spontaneous resolution of warts occurs rarely in adults. 16 A similar inverse relationship between age of subjects and response rates to wart treatment has been documented in the literature by Horn et al 17 in a 3-arm study that assessed the efficacy of antigen injection vs interferon injection vs control (isotonic sodium chloride solution) for the treatment of warts. In that study, the nonresponders tended to be older than the responders, and further analysis showed that age younger than 40 years was positively associated with probability of a response.…”