2011
DOI: 10.1007/s10646-011-0720-3
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Abstract: Polybrominated diphenyl ethers (PBDEs) are widely used as flame retardants around the world. Because of large production volumes, widespread usage and persistence, PBDEs are now ubiquitous environmental pollutants detected in a wide variety of environment media and human samples and therefore pose a significant public health concern. Deca-PBDE (BDE-209) is the only commercial PBDE mixture still allowed for use at present, and has been recently detected at high levels in human samples. However, few studies expl… Show more

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Cited by 94 publications
(63 citation statements)
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References 43 publications
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“…The net speed change in the 31.0 mg/L group from light period to dark period was also significantly increased. This typical behavior in the 31.0 mg/L group of low activity in normal light but hyperactivity in dark has also been observed in F1 larvae after long-term adult exposure to BDE-209 [22]. In addition, our results showed that PBDE exposure was associated with delayed transition in activity following photoperiod transition, which was also reported for 144 hpf zebrafish larvae treated with 1% ethanol [33].…”
Section: Discussionsupporting
confidence: 85%
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“…The net speed change in the 31.0 mg/L group from light period to dark period was also significantly increased. This typical behavior in the 31.0 mg/L group of low activity in normal light but hyperactivity in dark has also been observed in F1 larvae after long-term adult exposure to BDE-209 [22]. In addition, our results showed that PBDE exposure was associated with delayed transition in activity following photoperiod transition, which was also reported for 144 hpf zebrafish larvae treated with 1% ethanol [33].…”
Section: Discussionsupporting
confidence: 85%
“…Alterations in neurobehavioral performance have also been reported for killifish (Fundulus heteroclitus) embryos exposed to DE-71 [20]. Recently, behavioral studies have been carried out to examine the neurobehavioral effects of PBDEs in zebrafish [21][22][23]. These studies indicated that behavioral measurement is a sensitive indicator of PBDE-induced neurotoxicity.…”
Section: Introductionmentioning
confidence: 90%
“…In an experiment in which adult fathead minnows (Pimephales promelas) were fed daily for 25d with BDE-47, the condition factor of only the males was significantly reduced (P b 0.011) compared with controls (Muirhead et al, 2006). Contrary to that finding, longterm continuous exposure to BDE-209 was related to an increase in the condition factor in adult male zebrafish (Danio rerio), suggesting a potential link with obesity-related genes (He et al, 2011). In this LCR study, trans-chlordane, an extremely persistent organochlorine insecticide banned in 1988 (Keith, 1997), was the only compound found to associate with condition factor (ρ = −0.34556; P = 0.0527).…”
Section: Fish and Sitesmentioning
confidence: 74%
“…Similarly, BDE-47 was not related to GSI, yet it was negatively correlated with sperm motility in LSS (Table 3). The reduced GSI in male zebrafish exposed to BDE-209 indicated anti-androgenic effects by this congener (He et al, 2011). Because results indicate various modes of action on gonads and other reproductive parameters are apparent among exposures with individual PBDE and PCB congeners, heterogeneous reproductive and endocrine mechanisms are certainly transpiring where fish are exposed to complex chemical mixtures.…”
Section: Fish and Sitesmentioning
confidence: 97%
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