Chronic Urticaria Is Not Significantly Associated With Hepatitis C or Hepatitis G Infection

Cribier, B.; Santinelli, F.; Schmitt, Carine; Stoll‐Keller, Françoise; Grosshans, É

doi:10.1001/archderm.135.11.1335

Cited by 27 publications

(14 citation statements)

References 34 publications

(34 reference statements)

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“…The control groups consisted of patients with a different chronic inflammatory skin disease (chronic urticaria) and patients with malignant melanoma. Similar to lichen ruber planus, the discussion on hepatitis as a potential trigger in chronic urticaria is also highly controversial [17, 18]. There is no known correlation between malignant melanoma and hepatitis infection; this was consistent with the findings in our control group of patients with malignant melanoma.…”

Section: Discussionsupporting

confidence: 88%

Lichen planus and hepatitis virus infections: causal association?

Rübsam

Schroll

Weisenseel

et al. 2011

J Deutsche Derma Gesell

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LP is not specifically associated with hepatitis B or C antibodies in the Caucasian population of Germany. The higher prevalences of HBV antibodies found in LP and URT patients may be a reflection of age- and sex-related factors rather than disease-specific exposure to HBV infections. The increased prevalences seen in patients with LP or URT compared to MM patients may suggest that HBV infection serves as an unspecific trigger for a specific immune reaction of another origin.

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Section: Discussionsupporting

confidence: 88%

Lichen planus and hepatitis virus infections: causal association?

Rübsam

Schroll

Weisenseel

et al. 2011

J Deutsche Derma Gesell

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“…In three studies, the prevalence of HAV ranged from 0% (two studies) to 8.3% (one study) . The prevalence of hepatitis G virus (GBV‐C), in one study, was 1.8% . We did not find any reports on the prevalence of hepatitis D and E in patients with CSU.…”

Section: Resultsmentioning

confidence: 71%

Comorbidity of viral hepatitis and chronic spontaneous urticaria: A systematic review

Kolkhir

Pereverzina

Olisova

et al. 2018

Allergy

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Chronic viral infections including those by hepatitis B (CHB) virus and hepatitis C (CHC) virus have been reported to be comorbidities of chronic spontaneous urticaria (CSU). Here, we performed the first comprehensive review of the peer-reviewed literature (PubMed, Web of Science and Google Scholar) on the prevalence of CHB and CHC in patients with CSU and vice versa. The prevalence of CHB and CHC in CSU does not appear to be increased. Less than 5% and 2% of patients with CSU have markers of CHB and CHC, respectively, according to most of the 32 studies reviewed. Urticarial rash including CSU occurs in ≤3% of patients with CHC as reported by most of 20 studies analysed. Very few patients have been assessed for the effects of antiviral hepatitis treatment on their CSU, and two but not all reportedly showed improvement. Hepatitis B/C infections appear unlikely to be linked to CSU. We suggest that routine screening for these infections in patients with CSU is not relevant or cost-effective and should not be performed unless liver function tests are abnormal, risk factors or symptoms of viral hepatitis are present, or urticarial vasculitis is suspected.

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“…Individual studies in Japan found increased frequency of hepatitis C (HC) infection in CU patients. However, a study in Europe found no such association [10].…”

Section: Viral Hepatitismentioning

confidence: 95%

Chronic urticaria and systemic diseases

Zweiman

2003

Curr Allergy Asthma Rep

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Chronic Urticaria Is Not Significantly Associated With Hepatitis C or Hepatitis G Infection

Cited by 27 publications

References 34 publications

Lichen planus and hepatitis virus infections: causal association?

Lichen planus and hepatitis virus infections: causal association?

Comorbidity of viral hepatitis and chronic spontaneous urticaria: A systematic review

Chronic urticaria and systemic diseases

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