Chronic toxicity and carcinogenicity of olestra in Swiss CD-1 mice

Safety assessment of aditoprim acute, subchronic toxicity and mutagenicity studies

“…The pre‐set two‐sided P ‐value of <0.05 or 0.01 was taken as statistically significant. Values are expressed as means with their standard errors (Lindamood et al , ; Lafranconi et al , ; Takeda & Flood, ).…”

Safety assessment of aditoprim acute, subchronic toxicity and mutagenicity studies

“…The pre‐set two‐sided P ‐value of <0.05 or 0.01 was taken as statistically significant. Values are expressed as means with their standard errors (Lindamood et al , ; Lafranconi et al , ; Takeda & Flood, ).…”

Degradation of olestra, a non caloric fat replacer, by microorganisms isolated from activated sludge and other environments

“…Radiolabel absorption studies in rats have shown that olestra is essentially not absorbed from the GI tract (Miller et al 1995). Studies with mice, rats, and dogs fed olestra at levels up to 10% of the diet for 20-24 months have provided confirmation that olestra is not significantly absorbed by examining potential target organs for the presence of olestra (LaFranconi et al 1994;Miller et al 1991;Wood et al 1991).…”

Olestra: A Solution to Food Fat?

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Safety assessment of aditoprim acute, subchronic toxicity and mutagenicity studies

“…The pre‐set two‐sided P ‐value of <0.05 or 0.01 was taken as statistically significant. Values are expressed as means with their standard errors (Lindamood et al , ; Lafranconi et al , ; Takeda & Flood, ).…”

Degradation of olestra, a non caloric fat replacer, by microorganisms isolated from activated sludge and other environments

“…Radiolabel absorption studies in rats have shown that olestra is essentially not absorbed from the GI tract (Miller et al 1995). Studies with mice, rats, and dogs fed olestra at levels up to 10% of the diet for 20-24 months have provided confirmation that olestra is not significantly absorbed by examining potential target organs for the presence of olestra (LaFranconi et al 1994;Miller et al 1991;Wood et al 1991).…”

Olestra: A Solution to Food Fat?

“……”

Safety assessment of aditoprim acute, subchronic toxicity and mutagenicity studies

“…The pre‐set two‐sided P ‐value of <0.05 or 0.01 was taken as statistically significant. Values are expressed as means with their standard errors (Lindamood et al , ; Lafranconi et al , ; Takeda & Flood, ).…”

Degradation of olestra, a non caloric fat replacer, by microorganisms isolated from activated sludge and other environments

“…Radiolabel absorption studies in rats have shown that olestra is essentially not absorbed from the GI tract (Miller et al 1995). Studies with mice, rats, and dogs fed olestra at levels up to 10% of the diet for 20-24 months have provided confirmation that olestra is not significantly absorbed by examining potential target organs for the presence of olestra (LaFranconi et al 1994;Miller et al 1991;Wood et al 1991).…”

Olestra: A Solution to Food Fat?

“……”