Chronic rhinosinusitis: Epidemiology and medical management

Hamilos, Daniel L.

doi:10.1016/j.jaci.2011.08.004

Cited by 355 publications

(322 citation statements)

References 115 publications

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“…(8) reduced workplace productivity and serious medical treatment costs. (9,10) Identified several risk factors for CRS, including influenza vaccination, septal deviation and allergic rhinitis. Moreover, there were significantly increased prevalence of chronic rhinosinusitis in plant and machinery operators and assemblers, craft and related trade workers and the unemployed.…”

Section: Discussion:-mentioning

confidence: 99%

Prevalence of Chronic Rhino Sinusitis and It's Recurrent After Treatment Compare to Its Recurrent After Surgery at Saudi Arabia, 2016.

Abualnasr.¹,

Alattas.²,

Abualnasr.³

et al. 2017

IJAR

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Objectives:To assess the prevalence of Chronic Rhinosinusitis in Saudi Arabia, identify the most affected age group and Gender, assess the most common risk factors for Rhinosinusitis and determine recurrent of Rhinosinsitis after treatment and after surgery and to compare them. Methods: A cross-sectional study which was conducted electronically through a random sampling includes434 person from Saudi Arabia during 2016. The used questionnaire includes 20 questions and was formulated to include demographic aspects, clinical features, risk, medical and surgical history. The questionnaire items were designed and written to suit the tradition and the Islamic culture. Results: about half had infected with chronic sinusitis. 61.6% were females. 55.6% were between (21-30) years old. 31.9% of infected respondents still having the inflammation without complications for more than three months. 97.6% of infected respondents are treated using medical drugs.96.9% of the infected ones have the inflammation many times after having drugs as a way of treatment, while 3.1% of them have the inflammation many times after having surgical treatment but it is very important to clarify that the first case's percentage is much higher than the second; because most of the infected people use the medical drugs as a way of treatment not the surgical treatment.The most of our infected respondents weren't smokers. 61.6% of infected respondents suffer from sensitivity. 82.9% of infected respondents hadn't nasal polyps.

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Section: Discussion:-mentioning

confidence: 99%

Prevalence of Chronic Rhino Sinusitis and It's Recurrent After Treatment Compare to Its Recurrent After Surgery at Saudi Arabia, 2016.

Abualnasr.¹,

Alattas.²,

Abualnasr.³

et al. 2017

IJAR

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“…CRS has been recently divided into two subgroups: with and without nasal polyps (18). The majority of cases of CRS with nasal polyps show Th2-type inflammation with prominent accumulation of eosinophils in the nasal polyps and are thus called eosinophilic CRS (ECRS) (19). Histological Significance A substantial proportion of people have intractable chronic allergic diseases for which no curative treatment exists.…”

mentioning

confidence: 99%

Thy1⁺IL-7⁺lymphatic endothelial cells in iBALT provide a survival niche for memory T-helper cells in allergic airway inflammation

Shinoda

Hirahara

Iinuma

et al. 2016

Proc. Natl. Acad. Sci. U.S.A.

103

100

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Memory CD4 + T helper (Th) cells are central to long-term protection against pathogens, but they can also be pathogenic and drive chronic inflammatory disorders. How these pathogenic memory Th cells are maintained, particularly at sites of local inflammation, remains unclear. We found that ectopic lymphoid-like structures called inducible bronchus-associated lymphoid tissue (iBALT) are formed during chronic allergic inflammation in the lung, and that memory-type pathogenic Th2 (Tpath2) cells capable of driving allergic inflammation are maintained within the iBALT structures. The maintenance of memory Th2 cells within iBALT is supported by Thy1 + IL-7-producing lymphatic endothelial cells (LECs). The Thy1 + IL-7-producing LECs express IL-33 and T-cell-attracting chemokines CCL21 and CCL19. Moreover, ectopic lymphoid structures consisting of memory CD4 + T cells and IL-7 + IL-33 + LECs were found in nasal polyps of patients with eosinophilic chronic rhinosinusitis. Thus, Thy1 + IL-7-producing LECs control chronic allergic airway inflammation by providing a survival niche for memory-type Tpath2 cells.

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“…It is diagnosed subjectively on the basis of two or more of the following symptoms; nasal congestion, facial pain or pressure, nasal discharge, and a reduced sense of smell. Patients should also have objective evidence of disease, either directly with an endoscope or CT-imaging-this identifies nasal polyp presence [1].…”

Section: Discussionmentioning

confidence: 99%

Maxillary Sinusitis of Dental Origin

Patel¹,

Rachmanidou²

2015

JHS

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Abstract:We report a 53 year-old male who suffered 18 months of foul-smelling green nasal discharge, halitosis and a heavy discomfort behind his right eye. The symptoms were consistent with chronic rhinosinusitis. The patient had a right upper molar dental extraction shortly before the onset of symptoms. A radio-opaque foreign body was noted in his right maxillary sinus on CT. During surgery a tooth resembling foreign body was removed. The patient's symptoms completely resolved within weeks of the removal.

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Chronic rhinosinusitis: Epidemiology and medical management

Cited by 355 publications

References 115 publications

Prevalence of Chronic Rhino Sinusitis and It's Recurrent After Treatment Compare to Its Recurrent After Surgery at Saudi Arabia, 2016.

Prevalence of Chronic Rhino Sinusitis and It's Recurrent After Treatment Compare to Its Recurrent After Surgery at Saudi Arabia, 2016.

Thy1⁺IL-7⁺lymphatic endothelial cells in iBALT provide a survival niche for memory T-helper cells in allergic airway inflammation

Maxillary Sinusitis of Dental Origin

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Chronic rhinosinusitis: Epidemiology and medical management

Cited by 355 publications

References 115 publications

Prevalence of Chronic Rhino Sinusitis and It's Recurrent After Treatment Compare to Its Recurrent After Surgery at Saudi Arabia, 2016.

Prevalence of Chronic Rhino Sinusitis and It's Recurrent After Treatment Compare to Its Recurrent After Surgery at Saudi Arabia, 2016.

Thy1+IL-7+lymphatic endothelial cells in iBALT provide a survival niche for memory T-helper cells in allergic airway inflammation

Maxillary Sinusitis of Dental Origin

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Product

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About

Thy1⁺IL-7⁺lymphatic endothelial cells in iBALT provide a survival niche for memory T-helper cells in allergic airway inflammation