Chronic Obstructive Pulmonary Disease, Hospital Visits, and Comorbidities

Wheaton, Anne G.; Ford, Earl S.; Cunningham, Timothy J.; Croft, Janet B.

doi:10.1177/0898264314552419

Cited by 28 publications

(20 citation statements)

References 30 publications

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“…From a general point of view, cardiovascular disorders proved once again the most represented in COPD patients, with a percentage frequency absolutely comparable to that of other recent studies [ 3 , 7 – 9 , 19 , 24 ], even if with some differences, such as, congestive heath failure were most represented in females, and chronic cor pulmonale and arrhythmias in males. Ischemic heart disease were equally distributed in both sex and this result might be related to the ever increasing tobacco use among females in our country during the last decades.…”

Section: Discussionsupporting

confidence: 85%

Prevalence of different comorbidities in COPD patients by gender and GOLD stage

Negro

Bonadiman

Turco

2015

Multidiscip Respir Med

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BackgroundSeveral comorbidities frequently affect COPD progression. Aim of the study was to assess the prevalence of main comorbidities by gender and disease severity in a cohort of COPD patients referring for the first time to a specialist institution.MethodsThe study was a non-interventional, cross-sectional investigation carried out via automatic and anonymous selection from the institutional data base over the period 2012–2015. Inclusion criteria were: subjects of both sex aged ≥40 years; diagnosis of COPD according to GOLD guidelines 2014; the availability of a complete clinical record file. Variables collected were: lung function; smoking history; BMI; the Charlson Comorbidity Index (CCI); number and kind of comorbidities for each patient.ResultsAt least one comorbidity of clinical relevance was found in 78.6 % of patients, but at least two in 68.8 %, and three or more were found in 47.9 % of subjects. Mean CCI was 3.4 ± 1.6sd. The overall prevalence was 2.6 comorbidities per patient, but 2.5 in males, and 3.0 in females, respectively (p < 0.05). Cardio-vascular disorders were the most frequent, but significantly more frequent in males (44.7 vs 30.7 %, respectively), while the metabolic, the digestive and the osteo-articular disorders were prevailing in females (12.4 vs 9.2; 14.2 vs 4.8, and 6.0 vs 3.8, respectively). In particular, chronic cor pumonale and arrhythmias mainly prevailed in men and congestive heart failure in females, while arterial hypertension resulted equally distributed. As concerning respiratory disorders, pneumonia, pleural effusions and chronic respiratory failure were more frequently found in men, while bronchiectasis and asthma-COPD overlap syndrome (ACOS) in females. Anaemia, gall bladder stones, osteoporosis and spontaneous fractures mostly prevailed in females, while gastric disorders of inflammatory origin and arthrosis were more frequent in males. Cognition disorders, dementia and signs of degenerative brain disorders were more frequently found in men, while depression in females. Finally, lung cancer was at the first place in men, but at the second in females.ConclusionsAll comorbidities increased their prevalence progressively up to the last stage of COPD severity, except the cardio-vascular and the metabolic ones which dropped in the IV GOLD stage, presumably due to the high mortality rate in this severe COPD stage. The gender-dependency of comorbidities was confirmed in general terms, even if lung cancer proved a dramatic increase almost independently of sex.

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Section: Discussionsupporting

confidence: 85%

Prevalence of different comorbidities in COPD patients by gender and GOLD stage

Negro

Bonadiman

Turco

2015

Multidiscip Respir Med

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“…These medical conditions also commonly coexisted in patients with COPD [1,23,24,25]. However, the previous study was limited by inadequate control of coexisting medical conditions, and this might cause confounding bias when estimating the risk of stroke in patients with COPDe [9,10].…”

Section: Discussionmentioning

confidence: 99%

Risk of Stroke and Post-Stroke Adverse Events in Patients with Exacerbations of Chronic Obstructive Pulmonary Disease

et al. 2017

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BackgroundThe risk and outcomes of stroke in patients with chronic obstructive pulmonary disease exacerbations (COPDe) remain unclear. We examined whether patients with COPDe faced increased risk of stroke or post-stroke outcomes.MethodsUsing Taiwan’s National Health Insurance Research Database, we identified 1918 adults with COPDe and selected comparison cohorts of 3836 adults with COPD no exacerbations and 7672 adults without COPD who were frequency matched by age and sex in 2000–2008 (Study 1). Stroke event was identified during 2000–2013 follow-up period. Adjusted hazard ratios (HRs) and 95% confidence intervals (CIs) of stroke associated with COPDe were calculated. In a nested cohort study (Study 2) of 261686 new-diagnosed stroke patients in 2000–2009, we calculated adjusted odds ratios (ORs) and 95% CIs of adverse events after stroke in patients with COPDe.ResultsPatients with COPDe had increased stroke incidence, with an adjusted HR of 1.28 (95% CI, 1.03–1.59). In the Study 2, COPDe were associated with post-stroke mortality (OR, 1.34, 95% CI 1.20–1.52), epilepsy (OR, 1.43; 95% CI, (1.22–1.67), and pneumonia (OR, 1.50; 95% CI, 1.39–1.62). Previous intubation for COPD and inpatient admissions due to COPD were factors associated with post-stroke adverse events.ConclusionPatients who have had COPDe face increased risks of stroke and post-stroke adverse events.

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“…[2] However, among older adults living in care facilities, COPD prevalence was found to be higher among men compared to women, 14.8% vs 11.4%. [5] Racial disparities exist in the life course of individuals living with COPD. The prevalence of COPD is overall similar between Caucasian and African American adults, but is the lowest among Hispanics/Latinos and Asian American adults.…”

Section: Introductionmentioning

confidence: 99%

Prevalence of disability among adults with chronic obstructive pulmonary disease, Behavioral Risk Factor Surveillance System 2016–2017

2020

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Background The prevalence of disabilities is rising steadily, reflecting an aging population and an increasing burden of chronic conditions affecting quality of life. There are scant national data on the prevalence of disability among individuals with chronic obstructive pulmonary disease (COPD). The main objective was to estimate the prevalence of common disabilities among US-based individuals diagnosed with COPD. Methods Data from the BRFSS, a national telephone survey examining health-related behaviors in 2016-2017 were analyzed. The study population consisted of individuals with self-reported COPD (N = 38352 in 2016 and N = 35423 in 2017). The prevalence of disabilities in hearing, vision, cognition, mobility, and independent living were obtained and adjusted with sampling weights. Healthcare access measures were described by type of disability. Results Mobility disability had the highest prevalence of 45.9 (44.8-47.0) % in 2016 and 48.4 (47.3-49.5) % in 2017 among respondents with COPD. The prevalence of disabilities was highest among those 45-64 years old, except for hearing and cognition. Hearing disabilities were most prevalent among males with COPD while cognitive and mobility disabilities were most prevalent among females with COPD. While differences in the prevalence of disabilities were observed, access to health care was similar by disability type and age group among respondents. Conclusion Contrary to expectation, the highest prevalence of disabilities was found not to be among those 65 years old and above. Further research is needed to explain this age-specific shift in

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Chronic Obstructive Pulmonary Disease, Hospital Visits, and Comorbidities

Cited by 28 publications

References 30 publications

Prevalence of different comorbidities in COPD patients by gender and GOLD stage

Prevalence of different comorbidities in COPD patients by gender and GOLD stage

Risk of Stroke and Post-Stroke Adverse Events in Patients with Exacerbations of Chronic Obstructive Pulmonary Disease

Prevalence of disability among adults with chronic obstructive pulmonary disease, Behavioral Risk Factor Surveillance System 2016–2017

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