Chronic Latent Oral Moniliasis (Thrush)

Robinson, Saul S.; Tasker, Samuel

doi:10.1001/archderm.1947.01520010089009

Arch Derm Syphilol

1947

DOI: 10.1001/archderm.1947.01520010089009

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Chronic Latent Oral Moniliasis (Thrush)

Saul S. Robinson¹,

Samuel Tasker²

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1948

1988

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Cited by 10 publications

(1 citation statement)

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“…Scattered reports of malignant transformation occurring in chronic candidal lesions of the oral mucosa have appeared in the dental/medical literature for the past 70 years (1)(2)(3)(4)(5)(6)(7)(8)(9). Typically the malignant change would develop in longstanding white patches which histologically showed candidal hyphae embedded in a prominent, thickened parakeratin layer.…”

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confidence: 99%

Resolution of candidal lesions of the dorsal rat tongue by ketoconazole

Allen

Rossie

Haring

et al. 1988

J Oral Pathology Medicine

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The purpose of this study was to determine whether the mucosal alterations of the dorsal rat tongue produced by Candida albicans infection were reversible upon treatment with the antifungal drug ketoconazole. Following experimentally‐produced infection, 17 rats showed clinical evidence of persistent lesions over a period of 20 weeks. Eight of these animals were then treated with ketoconazole daily for 2 weeks (20 mg/kg/day). Appropriate non‐infected controls and ketoconazole‐only controls were also maintained. Five weeks after the ketoconazole treatment, all animals were killed and the dorsal tongues evaluated clinically and histologically. Control groups showed no abnormalities. Of the 8 animals in the treated‐lesion group, all showed lesional resolution, while only 2 of the 9 animals in the untreated‐lesion group showed resolution of their lesions (p=0.002). These findings indicate that the epithelial changes produced by this candidal isolate for this period of time are reversible.

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confidence: 99%

Resolution of candidal lesions of the dorsal rat tongue by ketoconazole

Allen

Rossie

Haring

et al. 1988

J Oral Pathology Medicine

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Candida endocarditis

Andriole¹,

Kravetz²,

Roberts³

et al. 1962

The American Journal of Medicine

158

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Oral pathology in relation to dental prosthesis

Proctor¹

1953

The Journal of Prosthetic Dentistry

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Chronic Latent Oral Moniliasis (Thrush)

Cited by 10 publications

References 4 publications

Resolution of candidal lesions of the dorsal rat tongue by ketoconazole

Resolution of candidal lesions of the dorsal rat tongue by ketoconazole

Candida endocarditis

Oral pathology in relation to dental prosthesis

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