Chronic cough and irritable larynx

Bucca, Caterina; Bugiani, Massimiliano; Culla, Beatrice; Guida, Giuseppe; Heffler, Enrico; Mietta, Sabrina; Moretto, Antonella; Rolla, Giovanni; Brussino, Luisa

doi:10.1016/j.jaci.2010.10.038

Cited by 64 publications

(47 citation statements)

References 39 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Differences in the inclusion criteria (foreign studies excluded patients with upper respiratory tract infections within 8 weeks of treatment as well as those who had received treatment with ACEI), case selection, regions, ethnicity, diet, and sample sizes might account for the discrepancies in the etiology distributions between Chinese and foreign studies. All the patients included in our study had previously been treated in other clinics or hospitals, and 80% of the 456 patients with CC had been misdiagnosed as having chronic bronchitis or chronic laryngitis, possibly because an irritable larynx is common in patients with CC (20). Another reason might be the limited knowledge of the basic-level medical staff, who often treat CC in the same manner as chronic bronchitis or chronic laryngitis.…”

Section: Discussionmentioning

confidence: 99%

Chronic cough: clinical characteristics and etiologies of 510 cases

Jiang

Huang

et al. 2016

Turk J Med Sci

View full text Add to dashboard Cite

Background/aim: To investigate the clinical features and underlying etiologies of chronic cough (CC).Materials and methods: Five hundred and ten CC patients were enrolled. The phases, characteristics and associated clinical manifestations of CC among the gastroesophageal reflux cough (GERC), cough-variant asthma (CVA), and upper airway cough syndrome (UACS) groups were compared, and the diagnostic values of each group were evaluated by multiple regression analysis.Results: In the 510 patients, 404 had CC with single etiology-GERC (n = 175), CVA (n = 134), and UACS (n = 95). The characteristic features of GERC included gastric acid backflow symptoms such as sour-tasting regurgitation, heartburn, endoscopic esophagitis, poststimulation cough, frequent throat clearing, daytime mono-cough, and feelings of heaviness and pain in the chest. Patients with CVA typically exhibited sensitivity to smog and other irritants; the cough occurred mostly at night, and was associated with positive bronchodilator and provocation test results. The typical features of UACS included a history and/or symptoms of rhinitis, retropharyngeal postnasal drip, and wet cough occurring mostly during the daytime. The diagnostic specificities of above factors were >70%. Conclusion:The most common causes of CC include GERC, CVA, and UACS, and their diagnosis is based on the characteristics of the underlying disease.

show abstract

Section: Discussionmentioning

confidence: 99%

Chronic cough: clinical characteristics and etiologies of 510 cases

Jiang

Huang

et al. 2016

Turk J Med Sci

View full text Add to dashboard Cite

show abstract

“…[12] Bucca ve ark. [15] kronik öksürük tanımlayan 372 olgunun diyagnostik dağılımına baktıklarında GÖR tanım-layan 62 olgu (%17) olduğunu bildirmişlerdir. [15] Gastroözofageal reflünün VLS bulguları çeşitli olup yaygın larengeal ödem, hiperemi, posterior farengeal hiperemi-lenfoid hiperplazi, larengeal kontakt ülserler, polip, granülom, interaritenoid ödem-hiperemi, reinke ödemi başta olmak üzere geniş bir yelpazeye sahiptir.…”

Section: Discussionunclassified

“…[15] kronik öksürük tanımlayan 372 olgunun diyagnostik dağılımına baktıklarında GÖR tanım-layan 62 olgu (%17) olduğunu bildirmişlerdir. [15] Gastroözofageal reflünün VLS bulguları çeşitli olup yaygın larengeal ödem, hiperemi, posterior farengeal hiperemi-lenfoid hiperplazi, larengeal kontakt ülserler, polip, granülom, interaritenoid ödem-hiperemi, reinke ödemi başta olmak üzere geniş bir yelpazeye sahiptir. [16] Bizim çalışmamızda da RSI 13 ve üzeri olan hasta sayısı 28 (%36.8) olup bu olgularda en sık görülen VLS bulguları olarak posterior komissür ödemi ve hiperemisi ilişkisi anlamlıdır.…”

Section: Discussionunclassified

Importance of laryngologic examination in chronic cough

Tüzüner

Demirci²,

Bilgin³

et al. 2014

Kulak Burun Bogaz Ihtis Derg

View full text Add to dashboard Cite

Amaç: Bu çalışmada akciğer muayenesi ve spirometrik bulguları normal olan kronik öksürük hastalarında otorinolarengoloji ile ilişkili etyolojik nedenlerin dağılımı araştırıldı ve bu hastalarda videolarengostroboskopik (VLS) muayenenin önemi vurgulandı. Hastalar ve Yöntemler:İki aydan uzun süren öksürük yakınmasıyla göğüs hastalıkları polikliniğine başvuran 76 hasta (31 erkek 45 kadın; ort. yaş 48.0±15.5 yıl; dağılım 18-83 yıl) çalışmaya dahil edildi. Hastalar göğüs hastalıkları uzmanı tarafından değerlendirildikten sonra kulak burun boğaz polikliniğine yönlendirildi. Öksürüğün altta yatan nedenini tespit etmek için hastaların detaylı öyküleri, fleksibl fiberoptik endoskopi ve VLS bulguları incelendi. Gastroözofageal reflü tanısında reflü semptom indeksi (RSİ) kullanıldı. Bulgular:Reflü semptom indeksi ≥13 olan grupta, 12 hastada (%42.9) posterior komissür ödemi, dört hastada (%14.3) posterior komissür hiperemisi saptandı. Bu bulgular, RSİ <13 grubundan istatistiksel olarak anlamlı şekilde yüksekti (sırasıyla p=0.006 ve p=0.016). Alerjik riniti olan hastaların grubu ile alerjik riniti olmayan hastaların grubu arasında VLS bulguları açısından anlamlı bir farklılık yoktu. Akut sinüzit bulguları olan hastalarda posterior komissürde mukopürülan sekresyon oranı, akut sinüzit bulguları olmayan hastalardan istatistiksel olarak yüksekti (p<0.001).Sonuç: Kronik öksürük pek çok farklı hastalığın yaygın bir semptomudur. Bu nedenle, tanı için multidisipliner yaklaşım önemlidir.Gastroözofageal reflü ve akut sinüzitin ayırıcı tanısında VLS değerli bir muayene yöntemidir.Anahtar Sözcükler: Kronik öksürük; gastroözofageal reflü; akut sinüzit; videolarengostroboskopi.Objectives: This study aims to investigate the distribution of etiologic factors related to otorhinolaryngology in chronic cough patients with normal lung examination and spirometric findings, and also highlight the importance of videolaryngostroboscopic (VLS) examination with these patients. Patients and Methods:Seventy-six patients (31 males, 45 females; mean age 48.0±15.5 years; range 18 to 83 year) who applied to pulmonology outpatient clinic with cough complaint for more than two months were included in the study. After being evaluated by a pulmonologist, patients were referred to otolaryngology outpatient clinic. To detect the underlying cause of cough, patients' detailed histories, and flexible fiberoptic endoscopy and VLS findings were reviewed. Reflux symptom index (RSI) was used for the diagnosis of gastroesophageal reflux. Results:In RSI ≥13 group, posterior commissure edema was detected in 12 patients (42.9%), and posterior commissure hyperemia was detected in four patients (14.3%). These findings were statistically significantly higher than RSI <13 group (p=0.006 and p=0.016, respectively). No significant difference was present between the group of patients with allergic rhinitis and the group of patients without allergic rhinitis in terms of VLS findings. Mucopurulent secretion rate in posterior commissure in patients with acute sinusitis findings was s...

show abstract

“…Noteworthy reviews on CRS published in 2011 include a review on chronic cough and irritable larynx 32 and CRS reviews in the October issue of the Journal on epidemiology and management, 33 genetics and phenotyping, 34 and pathogenesis. 35 Other reviews published elsewhere include a very useful comparison of guidelines on CRS management 36 and Cochrane reviews showing no evidence of benefit for topical or systemic antifungal agents in patients with CRS, 37 confirming the benefit of nasal steroids in patients with CRSsNP, 38 and suggesting that systemic steroids can improve symptoms of patients with acute sinusitis in the primary care setting.…”

Section: Managementmentioning

confidence: 99%