Chronic Behavioral and Neurochemical Effects of Four Novel N-Benzyl-2-phenylethylamine Derivatives Recently Identified as “Psychoactive” in Adult Zebrafish Screens
Nikita P. Ilyin,
Arslan D. Nabiullin,
Anna D. Kozlova
et al.
Abstract:Potently affecting human and animal brain and behavior, hallucinogenic drugs have recently emerged as potentially promising agents in psychopharmacotherapy. Complementing laboratory rodents, the zebrafish (Danio rerio) is a powerful model organism for screening neuroactive drugs, including hallucinogens. Here, we tested four novel N-benzyl-2-phenylethylamine (NBPEA) derivatives with 2,4-and 3,4-dimethoxy substitutions in the phenethylamine moiety and the −F, −Cl, and −OCF 3 substitutions in the ortho position … Show more
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