Chromoblastomycosis: an exuberant case

Abstract

Chromoblastomycosis is a chronic subcutaneous mycotic infection caused by dematiaceous saprophytic moulds. The most frequently isolated agent is Fonsecae pedrosoi. This article reports a case of a man from the Amazon region in Northern Brazil who presented with a lesion of 12 months' duration, which gradually increased in size until covering the majority of his right leg. A successful treatment with itraconazole was performed.

Cromoblastomicosis: características clínicas y microbiológicas de una enfermedad desatendida

“…Sin embargo, a pesar de la cronicidad, postergación de tratamiento específico y que uno de ellos presentaba www.sochinf.cl Caso Clínico diabetes mellitus como co-morbilidad, ninguno presentó complicaciones. Esto contrasta con casos en Brasil y Perú, donde los pacientes inicialmente diagnosticados como leishmaniasis, presentaron cromoblastomicosis diseminada 6,11 . La observación de células muriformes (5 a 12 um) en muestras clínicas es confirmatorio de cromoblastomicosis.…”

Annular atrophic plaque over the arm

“…[ 2 3 4 5 ] The diagnosis of chromoblastomycosis is done with the help of microscopy, culture, histopathology/cytological, and molecular techniques. [ 1 2 3 4 ] Direct microscopic examination of skin scraping/crust with 10% KOH, especially calcofluor and other fluorochromes stains demonstrate thick-walled round fungal sclerotic bodies. The confirmation of diagnosis and further speciation can be done by culture on Sabouraud's dextrose agar containing antimicrobials incubated at 25°C, which produces colony of melanized fungus over 2–4 weeks.…”