2020
DOI: 10.3390/jcm9020595
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Abstract: Remarkable improvements in optical coherence tomography (OCT) technology have resulted in highly sophisticated, noninvasive machines allowing detailed and advanced morphological evaluation of all retinal and choroidal layers. Postproduction semiautomated imaging analysis with dedicated public-domain software allows precise quantitative analysis of binarized OCT images. In this regard, the choroidal vascularity index (CVI) is emerging as a new imaging tool for the measurement and analysis of the choroidal vascu… Show more

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Cited by 144 publications
(99 citation statements)
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References 91 publications
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“…In agreement with these previous interpretations of HF and CVI, the presence of a high number of choroidal HF and low CVI values, this latter representing intense choroidal congestion, can be interpreted as structural OCT signs of increased chorioretinal inflammation [ 22 ]. From this perspective, the categorization of DME eyes according to these structural OCT biomarkers of inflammation may have a role when making the proper choice of intravitreal therapeutic strategy in the DME setting.…”
Section: Discussionsupporting
confidence: 86%
“…In agreement with these previous interpretations of HF and CVI, the presence of a high number of choroidal HF and low CVI values, this latter representing intense choroidal congestion, can be interpreted as structural OCT signs of increased chorioretinal inflammation [ 22 ]. From this perspective, the categorization of DME eyes according to these structural OCT biomarkers of inflammation may have a role when making the proper choice of intravitreal therapeutic strategy in the DME setting.…”
Section: Discussionsupporting
confidence: 86%
“…The choroidal vascularity index (CVI) is a novel OCT parameter for measuring the vasculature status of the choroid [ 55 ]. The CVI is a term introduced by Agrawal et al and represents the ratio of choroidal luminal area to total choroidal area [ 56 ].…”
Section: Developmentmentioning
confidence: 99%
“…After segmentation of the choroidal area, the hyporeflective blood vessel lumina are distinguished from the hyperreflective stromal tissue. The reliability of the results from graphical analysis strongly depends on the OCT technology (scan depth, scan resolution, and image contrast) 11 , 22 but also on subject factors (absolute choroidal thickness and the pigmentation of the retinal pigment epithelium). 23 , 24 Therefore, these parameters influence the repeatability of ChT and CVI measurements.…”
Section: Introductionmentioning
confidence: 99%