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Cited by 37 publications
(39 citation statements)
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“…CSCR is considered part of the pachychoroid disease spectrum [ 12 ]. Dilated and congested choroidal vessels (pachyvessel) increased choroid thickness and leakage through RPE resulting in subretinal fluid accumulation and neurosensory detachment [ 13 , 14 ]. It is believed that the role of PDT in the treatment of CSCR is through the production of free radicals and damage to the vascular endothelium, resulting in thrombosis and obstruction of dilated choroidal vessels [ 15 , 16 ].…”
Section: Discussionmentioning
confidence: 99%
“…CSCR is considered part of the pachychoroid disease spectrum [ 12 ]. Dilated and congested choroidal vessels (pachyvessel) increased choroid thickness and leakage through RPE resulting in subretinal fluid accumulation and neurosensory detachment [ 13 , 14 ]. It is believed that the role of PDT in the treatment of CSCR is through the production of free radicals and damage to the vascular endothelium, resulting in thrombosis and obstruction of dilated choroidal vessels [ 15 , 16 ].…”
Section: Discussionmentioning
confidence: 99%
“…Furthermore, Iovino et al observed a sustained decrease in central macular thickness and subfoveal choroidal thickness after PDT of chronic CSC, as well as a decrease in total choroidal area and luminal choroidal area at a 1-month follow-up interval [ 34 ].We reported that these results support the hypothesis that PDT targets large choroidal vessels and causes contraction and total choroidal volume reduction. Simultaneous evaluation of blood flow measurements using LSFG and choroidal structural changes using OCT and ICGA could explain and depict the pathophysiology of CSC.…”
Section: Discussionmentioning
confidence: 99%
“…Previous work by Iovino et al has shown that reduction in luminal and total choroidal area was notable only at 1 month follow up suggestive of a transient, diffuse choroidal vascular remodeling. 16 The difference in variability of CT and CVI was also derived using CV used as a measure of dispersion of data. CVI values (CV = 0.08) showed less variation compared to CT (CV: 0.25) which is consistent with our previous published results in normal eyes.…”
Section: Discussionmentioning
confidence: 99%