Chondromyxoid fibroma of the mandible: Case report and review of the literature

Fomete, Benjamin; Adeosun, O. O.; Awelimobor, Daniel I.; Olayemi, L.

doi:10.4103/2231-0746.133072

Cited by 23 publications

(6 citation statements)

References 5 publications

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“…Ameloblastic fibroma was a close differential diagnosis however, the characteristic ameloblastic epithelium depicts reversely polarized nuclei in the peripheral layer of tall columnar cells, which was not seen in our case . Chondromyxoid fibroma may involve the jaw bones but this lesion shows well defined borders on radiology and will also show chondroid areas on microscopy . Myxoid nerve sheath tumors were ruled out by absence of long wavy nuclei .…”

Section: Discussionmentioning

confidence: 50%

Cytological findings of odontogenic myxofibroma: A diagnostic dilemma

Khare

Joshi

Majumdar

et al. 2016

Diagnostic Cytopathology

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Odontogenic myxofibroma represents a rare slow-growing benign neoplasm, which usually occurs in the second and third decades of life and rarely in children or adults over 50 years of age. Myxomas in general represent from 2.3% to 17.7% of all odontogenic tumors, and myxofibromas represent a small number of all myxomas. Limited evidence is present in literature regarding the cytological diagnosis of odontogenic myxoma/myxofibroma. We hereby report the cytomorphological features of a histologically confirmed case of odontogenic myxofibroma and the pitfalls of the cytological diagnosis. A painless jaw swelling in a young boy was aspirated. Scanty mucoid material was obtained. Cytology Smears were moderately cellular and showed a population comprising predominantly of singly scattered plump to fusiform cells with bipolar cytoplasmic processes showing mild to moderate atypia embedded within dense myxoid matrix and another population of cells arranged in clusters. Case was interpreted as low grade mesenchymal tumor. Subsequent biopsy confirmed it as odontogenic myxofibroma arising in a odontogenic keratocyst. Precise interpretation of intraosseous jaw lesions FNAC may not always be possible, but an attempt should be made to broadly classify the lesion as an inflammatory lesion, cystic lesion, giant cell lesion, fibro-osseous lesion or as an odontogenic tumor. If dual population of odontogenic epithelium and mesenchymal cells embedded in myxoid matrix are identified in such aspirates, a possibility of myxoid odontogenic tumor may be suggested. Triple correlation of cytological, clinical and radiological findings can guide the surgeon for taking appropriate therapeutic decisions.

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Section: Discussionmentioning

confidence: 50%

Cytological findings of odontogenic myxofibroma: A diagnostic dilemma

Khare

Joshi

Majumdar

et al. 2016

Diagnostic Cytopathology

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“…We conducted a search of the literature on lip PAs (in Japan and worldwide) and found 35 cases described in 31 reports since 2000 (Table 2) (10,11,14-17,19-22,26-39,41). Of the 35 past cases of lip PA, 30 (85.7%) were in the upper lip (10,11,13,15,17,(19)(20)(21)(23)(24)(25)(26)(28)(29)(30)(32)(33)(34)(35)(36)(37)(38)(39)(40)(41) and only five (14.3%) were in the lower lip (14,16,22,27,31). The male-tofemale ratio of the lip PAs was 4:3 (a nonsignificant difference), and the age range was from 10 to 72 years (Table 2).…”

Section: Discussionmentioning

confidence: 99%

Lip pleomorphic adenomas: case series and literature review

Umemori¹,

Ono²,

Kanemoto³

et al. 2022

Gland Surg

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Background: Pleomorphic adenoma (PA) is the most frequent benign salivary gland tumor, but a lip PA is rare. Although this tumor may be definitively diagnosed by imaging or a tissue biopsy if it is reasonably large, PAs on the lip are relatively small, and they present findings that are similar to those of other lip lesions, which can make a preoperative diagnosis difficult. Methods:We analyzed all PAs in the oral region and lesions on the lips treated in our department over the past 20 years, and we discuss them together with the relevant literature.Results: We found that 11.8% (n=6) of the PAs occurred on a lip (upper lip: 9.8%, lower lip: 2.0%), and ~1% of all mass lesions of the lips were PAs. The average size of the lip PAs was 1.5±0.7 cm (range, 0.7-2.2 cm).For preoperative diagnostic assistance, ultrasonography (US) (n=4), magnetic resonance (MR) (n=3), or no imaging (n=2) was used. An excisional biopsy was performed in all cases, and to date, no recurrence or malignant transformation has been observed.Conclusions: Lip PA is relatively rare. Because almost all of these lesions are small, a preoperative diagnosis is more difficult compared to palatal lesions. This tumor is also prone to long-term neglect and has the potential for recurrence and malignant transformation. It is thus necessary to perform an excision that includes the capsule and surrounding tissues, and careful postoperative follow-up should be continued.

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“…as opposed to a holistic view of salivary gland tumors, and therefore, they need to be summarized and visualized to be easily comparable in terms of the epidemiology, therapy, and prognosis. Some different reviews concerning salivary gland tumors have been published in the last two centuries [1], [4], [5], [6], [7], [8], [9], [10], [11], [12], [13], [14], [15], [16], [17], [18] most of which discuss the entities or diagnostic or prognostic aspects and principal therapeutic strategies in detail. However, there is no research article that described an overview of the gender-specific distribution as well as country-specific differences for those tumors.…”

Section: Introductionmentioning

confidence: 99%