Cholangioscopy and probe‐based confocal laser endomicroscopy for real‐time diagnosis of intraductal papillary mucinous neoplasm of the bile duct

Wen, Ji; Ji, Jianmei; Gong, Bo

doi:10.1111/den.13472

Cited by 4 publications

(3 citation statements)

References 5 publications

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“…We considered the black strip-like structures found in the neck of the gallbladder are similar to the collagen found in the pCLE examination of the bile duct [21]. The suspected Aschoff-Rokitansky sinus structures found in the neck of the gallbladder may provide a new basis for further studies related to gallstone recurrence.…”

Section: Discussionmentioning

confidence: 99%

“…The shape of probe-based CLE (pCLE) and needle-based CLE makes possible to pass through most kinds of endoscopic channels, which greatly increases the scope usage. Currently, this tech-nique is used in diagnosis in various digestive organs, including esophagus, stomach, duodenum, colon-rectum, biliary and pancreatic duct, pancreas, and liver [14][15][16][17][18][19][20][21][22][23][24][25]. Its accuracy in diagnosis of Barrett's esophagus, pancreatic cystic degeneration, bile duct stricture, and other diseases is comparable to the histological diagnosis.…”

Section: Confocal Laser Endomicroscopymentioning

confidence: 99%

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The Application of Probe-Based Confocal Laser Endomicroscopy as a Diagnostic Tool in Choledochoscopic Gallbladder-Preserving Surgery

Tang

Jia

Dang

et al. 2022

Dig Dis

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Background and Aims: Choledochoscopic gallbladder-preserving surgery（CGPS） has the advantage of treating benign gallbladder diseases on the premise of gallbladder preservation. However, it has no reliable preoperative diagnosis if the gallbladder is benign. Probe-based confocal laser endomicroscopy (pCLE) can obtain real-time and clear endoscopic images at the cell level in vivo.It is widely used in the diagnosis of digestive system diseases，but not in gallbladder diseases yet. We applied these two technologies in a complementary way into the diagnosis of gallbladder diseases and thereby lifted the reliability of CGPS. Methods: We retrospectively analyzed the total twenty-eight patients with the indication of CGPS with introparative pCLE scan referred to The Second Affiliated Hospital of Baotou Medical College between October 2019 and July 2020. The intraoperative pCLE results were compared with the postoperative pathology in various gallbladder diseases. Results: We compared the intraoperative pCLE diagnosis with the postoperative pathological diagnosis, and found a complete match without exception in both sensitivity and specificity. Conclusions: Based on our investigation, pCLE can provide the same accuracy as the tranditional pathology in the diagnosis of gallbladder diseases with the additional advantages like noninvasive, real-time, and instancy.This study serves to validate the correlation between CLE and histology. It holds a broad prospect in the application of pCLE as an intraoperative diagnosis in CGPS.

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Section: Discussionmentioning

confidence: 99%

Section: Confocal Laser Endomicroscopymentioning

confidence: 99%

The Application of Probe-Based Confocal Laser Endomicroscopy as a Diagnostic Tool in Choledochoscopic Gallbladder-Preserving Surgery

Tang

Jia

Dang

et al. 2022

Dig Dis

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“…Most cases of IPNB are diagnosed by examining surgical specimens. IPNB remains diagnostic challenge 3,4 . Here, we report a case of IPNB, which was directly diagnosed by performing upper gastrointestinal endoscopy through a duodenobiliary fistula.…”

Section: Figurementioning

confidence: 97%

Intraductal papillary neoplasm of the bile duct diagnosed by upper gastrointestinal endoscopy through a duodenobiliary fistula

Sakai

Fujigaki

Kodama

2020

Digestive Endoscopy

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Clinicopathological Features of 12 Cases of Intraductal Papillary Neoplasm of the Bile Duct: A Case Series

Gu,

Jin,

Wang

et al. 2024

Indian J Surg

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Cholangioscopy and probe‐based confocal laser endomicroscopy for real‐time diagnosis of intraductal papillary mucinous neoplasm of the bile duct

Cited by 4 publications

References 5 publications

The Application of Probe-Based Confocal Laser Endomicroscopy as a Diagnostic Tool in Choledochoscopic Gallbladder-Preserving Surgery

The Application of Probe-Based Confocal Laser Endomicroscopy as a Diagnostic Tool in Choledochoscopic Gallbladder-Preserving Surgery

Intraductal papillary neoplasm of the bile duct diagnosed by upper gastrointestinal endoscopy through a duodenobiliary fistula

Clinicopathological Features of 12 Cases of Intraductal Papillary Neoplasm of the Bile Duct: A Case Series

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