Chitosan wound dressing with hexagonal silver nanoparticles for hyperthermia and enhanced delivery of small molecules

Levi‐Polyachenko, Nicole; Jacob, Reuben; Day, Cyn­thia S.; Kuthirummal, Narayanan

doi:10.1016/j.colsurfb.2016.02.038

Cited by 62 publications

(27 citation statements)

References 58 publications

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“…4,17,18 A large number of previous studies have shown that, compared with the silver ions, the cytotoxicity of AgNPs has been greatly decreased; however, AgNPs still induce cell damage through induction of apoptosis. [19][20][21] The cytotoxicity of AgNPs could be influenced by particle size, surface-stabilizing agents, pH, and some other factors.…”

Section: Discussionmentioning

confidence: 99%

“…In addition, AgNPs/chitosan materials could promote wound healing. 3,17,[28][29][30] In comparison with long-chain high molecular weight chitosan, the short-chain LMWC is better in terms of water solubility and biocompatibility. Besides, it has been confirmed that LMWC enhances the physical and chemical stability of many drugs such as insulin 31 and siRNA, 32 and works as a suitable carrier for the delivery and controlled release of drugs.…”

Section: Discussionmentioning

confidence: 99%

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Low molecular weight chitosan-coated silver nanoparticles are effective for the treatment of MRSA-infected wounds

Peng¹,

Song²,

Yang³

et al. 2017

IJN

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Low molecular weight chitosan-coated silver nanoparticles are effective for the treatment of MRSA-infected wounds

Peng¹,

Song²,

Yang³

et al. 2017

IJN

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“…Further, CS films with hexagonal silver nanoparticles that generate heat and exhibit enhanced drug delivery properties when illuminated by infrared light have been synthesized (Table 1) [40]. These materials were found to be suitable for healing dermal wounds because they not only facilitated cell proliferation and mitigated bacterial infections but also promoted the delivery of small molecules into the cells.…”

Section: Scaffolds From Natural Polymersmentioning

confidence: 99%

Progress in development of bioderived materials for dermal wound healing

Huang

Xie

2017

Regenerative Biomaterials

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Treatment of acute and chronic wounds is one of the primary challenges faced by doctors. Bioderived materials have significant potential clinical value in tissue injury treatment and defect reconstruction. Various strategies, including drug loading, addition of metallic element(s), cross-linking and combining two or more distinct types of materials with complementary features, have been used to synthesize more suitable materials for wound healing. In this review, we describe the recent developments made in the processing of bioderived materials employed for cutaneous wound healing, including newly developed materials such as keratin and soy protein. The focus was on the key properties of the bioderived materials that have shown great promise in improving wound healing, restoration and reconstruction. With their good biocompatibility, nontoxic catabolites, microinflammation characteristics, as well as their ability to induce tissue regeneration and reparation, the bioderived materials have great potential for skin tissue repair.

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“…Combination of antimicrobial and photothermal therapies is useful against a variety of resistant bacteria . Moreover, mild hyperthermia has been shown to promote wound healing by increasing blood flow and also enhancing the intracellular delivery of active substances . To carry out the work, we hypothesized also that the gold counterion may play a role in the Au NPs formation process by altering the pH or the stability of the growing particles, and thus two gold salts having different counterions were investigated.…”

Section: Introductionmentioning

confidence: 99%

Poly(vinyl alcohol) triggers Au nanoparticles formation for near‐infrared radiation‐responsive gels and nanofibers

Álvarez-Lorenzo

Mayo‐Olveira

Barbosa

et al. 2019

J of Applied Polymer Sci

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The capability of poly(vinyl alcohol) (PVA) to reduce noble metal ions and, in turn, to prepare one‐step hybrid systems that exhibit near‐infrared radiation (NIR) light‐responsiveness has been barely explored. The aim of this work was to elucidate whether gold nanoparticles (Au NPs) could be spontaneously formed in PVA gels suitable to be used as syringeable depots or to prepare electrospun nanofibers. To check the hypothesis of that the gold counterion may play a role in the Au NPs formation process, two different gold salts (HAuCl4 and AuAc3) were used. Localized surface plasmon resonance bands were monitored during the incubation of PVA‐gold salt gels, and the photoresponsive capability of the newly formed Au NPs inside gels was investigated during laser irradiation at 808 nm. HET‐CAM assay suggested good biocompatibility. Then, the feasibility of producing electrospun hybrid PVA‐based mats that exhibit light‐responsive photothermal features was explored here for the first time. © 2019 Wiley Periodicals, Inc. J. Appl. Polym. Sci. 2020, 137, 48811.

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Chitosan wound dressing with hexagonal silver nanoparticles for hyperthermia and enhanced delivery of small molecules

Cited by 62 publications

References 58 publications

Low molecular weight chitosan-coated silver nanoparticles are effective for the treatment of MRSA-infected wounds

Low molecular weight chitosan-coated silver nanoparticles are effective for the treatment of MRSA-infected wounds

Progress in development of bioderived materials for dermal wound healing

Poly(vinyl alcohol) triggers Au nanoparticles formation for near‐infrared radiation‐responsive gels and nanofibers

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