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Cited by 35 publications
(33 citation statements)
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“…Empty nanoparticles (CW) without TTI were also prepared, using a 1:1 ( w / w ) ratio of encapsulating agents. The chitosan purification step was performed based on Kumari et al [21] with modifications proposed by Queiroz et al [16].…”
Section: Methodsmentioning
confidence: 99%
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“…Empty nanoparticles (CW) without TTI were also prepared, using a 1:1 ( w / w ) ratio of encapsulating agents. The chitosan purification step was performed based on Kumari et al [21] with modifications proposed by Queiroz et al [16].…”
Section: Methodsmentioning
confidence: 99%
“…Both nanoformulations (ECW and CW) were characterized by scanning electron microscopy (SEM), laser diffraction (LD), and Fourier transform infrared spectroscopy (FTIR), according to Queiroz et al [16], with few modifications in LD. To measure the diameter and the polydispersity index (PI), the dispersions containing the nanoparticles, previously crosslinked in triplicate, were filtered, and the precipitates were dispersed in 4 mL of water and analyzed in a NanoBrookZetaPlus Zeta Potential Analyzer.…”
Section: Methodsmentioning
confidence: 99%
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“…The combination of the encapsulating agents showed excellent incorporation efficiency and TTI stability. In addition, encapsulation in chitosan and whey protein promoted the reduction of the half maximal inhibitory concentration (IC50) and preserved inhibitory activity at temperatures up to 80 °C compared to isolated agents, showing that encapsulation is an interesting strategy to improve the function and stability of TTI 98 .…”
Section: Trypsin Inhibitors In the Treatment Of Chronic Diseases: Chamentioning
confidence: 99%