Chitosan Nanoparticles: Preparation, Characterization, and Applications

Perera, U. M. S. P.; Rajapakse, Niranjan

doi:10.1007/978-1-4614-9590-1_18

Cited by 27 publications

(15 citation statements)

References 49 publications

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“…Changing the basic structure of chitosan give an opportunity to obtain derivatives with a wide range of properties and consequently more application can be used [ 17 ]). One of the modern technologies is developing of chitosan micro-particles followed by nano-form, confirming the effective uses in many industries [ 18 ]. Although, many researches proofed the safety of chitosan for consumption either in food or drug sectors, there are no more available studies assess the toxicity of nano-chitosan particularly that derived from fungal source.…”

Section: Introductionmentioning

confidence: 99%

Bio-evaluation of crustacean and fungal nano-chitosan for applying as food ingredient

et al. 2018

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Section: Introductionmentioning

confidence: 99%

Bio-evaluation of crustacean and fungal nano-chitosan for applying as food ingredient

et al. 2018

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“…). It is accepted that CSNP‐based films can be effectively used in the food industry, as they provide various benefits, including good edibility, aesthetically pleasing appearance, barrier properties against pathogenic microorganisms, nontoxicity and low cost (Perera and Rajapaks ).…”

Section: Introductionmentioning

confidence: 99%

“…In the food industry, the main focus was to develop CSNPs-based edible films to be used as packaging material (Chang et al 2010;De Moura et al 2011;Martelli et al 2013;Hosseini et al 2015b). It is accepted that CSNP-based films can be effectively used in the food industry, as they provide various benefits, including good edibility, aesthetically pleasing appearance, barrier properties against pathogenic microorganisms, nontoxicity and low cost (Perera and Rajapaks 2014).…”

Section: Introductionmentioning

confidence: 99%

Preparation and Characterization of Chitosan Nanoparticles‐Loaded Fish Gelatin‐Based Edible Films

Hosseini

Rezaei

Zandi

et al. 2015

J Food Process Engineering

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Bio-based nanocomposite films were obtained from fish gelatin (FG) and different amounts of chitosan nanoparticles (CSNPs) (0, 2, 6 and 8% w/w) with diameters ranging from 40 to 80 nm. The influence of nanoparticles on the surface morphology, physicochemical properties, crystalline structure and thermal stability of FG was investigated. The surface morphology assay showed a considerable increase in roughness parameters by incorporating the nanoparticles in FG matrix. Contact angle measurements ranged from about 45C to 60-97C as filler concentration increased, indicating that reinforced films had higher superficial hydrophobicity than neat FG ones. The X-ray diffraction results also suggested a higher crystallinity in FG matrix due to CSNPs nucleating effect. The glass transition of the nanocomposites was shifted to lower temperatures with respect to the pure FG. Thermal stability tended to increase in accordance with CSNPs content, in which the highest shift of degradation temperature was observed at 6% (w/w) loading content. PRACTICAL APPLICATIONSIn recent years, bio-based polymers have attracted more and more attention due to growing environmental concern and decreasing reserve of fossil fuel. This recent evolution encourages researchers and industries to develop novel materials labeled as "environment friendly." This study investigates the preparation and characterization of eco-friendly fish gelatin-based composite reinforced with chitosan nanoparticles, as a substitution of plastic packaging materials with the goal of decreasing environmental pollution.

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“…Afterward, the separation and purification of the particles are performed by either filtration or centrifugation, followed by successive washing with hot and cold water. Another (alternative) method uses a sodium sulfate solution which is added dropwise to an acidic solution of CS containing surfactant while undergoing stirring and continuous sonication for 30 min [100].…”

Section: Precipitation/coacervationmentioning

confidence: 99%

Advances in Chitosan-Based Nanoparticles for Drug Delivery

Mikušová

Mikuš

2021

IJMS

244

120

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Nanoparticles (NPs) have an outstanding position in pharmaceutical, biological, and medical disciplines. Polymeric NPs based on chitosan (CS) can act as excellent drug carriers because of some intrinsic beneficial properties including biocompatibility, biodegradability, non-toxicity, bioactivity, easy preparation, and targeting specificity. Drug transport and release from CS-based particulate systems depend on the extent of cross-linking, morphology, size, and density of the particulate system, as well as physicochemical properties of the drug. All these aspects have to be considered when developing new CS-based NPs as potential drug delivery systems. This comprehensive review is summarizing and discussing recent advances in CS-based NPs being developed and examined for drug delivery. From this point of view, an enhancement of CS properties by its modification is presented. An enhancement in drug delivery by CS NPs is discussed in detail focusing on (i) a brief summarization of basic characteristics of CS NPs, (ii) a categorization of preparation procedures used for CS NPs involving also recent improvements in production schemes of conventional as well as novel CS NPs, (iii) a categorization and evaluation of CS-based-nanocomposites involving their production schemes with organic polymers and inorganic material, and (iv) very recent implementations of CS NPs and nanocomposites in drug delivery.

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Chitosan Nanoparticles: Preparation, Characterization, and Applications

Cited by 27 publications

References 49 publications

Bio-evaluation of crustacean and fungal nano-chitosan for applying as food ingredient

Bio-evaluation of crustacean and fungal nano-chitosan for applying as food ingredient

Preparation and Characterization of Chitosan Nanoparticles‐Loaded Fish Gelatin‐Based Edible Films

Advances in Chitosan-Based Nanoparticles for Drug Delivery

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