Chitosan based modified polymers designed to enhance membrane permeation capability

Lusiana, Retno Ariadi; Sangkota, Vivi Dia A.; Sasongko, Nurwarrohman Andre; Santosa, Sri Juari; Othman, Mohd Hafiz Dzarfan

doi:10.1088/1757-899x/509/1/012122

Cited by 2 publications

(4 citation statements)

References 9 publications

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“…The specific spectra PSf -PEG / CS (HPPs) membrane was shown by a peak in the wavenumber of 1320 cm 1 to show C-N ' s absorption. Furthermore, absorption at 3780 -3400 cm 1 indicated the strain of -O-H of chitosan, overlapping between -N-H and -O-H, strength peak of 1582 cm -1 indicates amide -N-H and -C-OH could be observed at 2300 cm 1 [ 15 ].…”

Section: Functional Groups Analysis Using Ftirmentioning

confidence: 97%

“…Further modification with chitosan also shows a tendency to decrease the membrane contact angle. According to Lusiana et al [ 15 ], the size of the contact angle produced is due to surface tension between the membrane and water contact angle.…”

Section: Characterizationmentioning

confidence: 99%

“…However, dilute acetic acid has a high-water content, a nonsolvent system of PSf in the solidification process. In dilute acid , chitosan is protonated to form -NH2 positive charge -NH 3 + [ 15 ]. To form a bond between the two compounds, the PSf should be modified to form polyanion.…”

Section: Introductionmentioning

confidence: 99%

“…Code of membranes a wavelength of 430 nm. The permeation of membrane is calculated using Equation (2)[ 15 ]:…”

mentioning

confidence: 99%

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In-Vitro Study of Polysulfone-polyethylene glycol/chitosan (PEG-PSf/CS) Membranes for Urea and Creatinine Permeation

et al. 2020

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High concentrations of creatinine and urea in the blood can be removed by dialysis using semipermeable membranes that are selective for certain species and hold other species through diffusion processes. This ability requires a membrane that has an active side, which functions as a targeted species identifier. The membrane must be biocompatible because the membrane will be in direct contact with the body’s biological systems. The membrane material that is made must be acceptable to the blood system so that there is no rejection from the body and have a large contact area to obtain an effective diffusion process. For this reason, a hollow fiber membrane (HFM) is needed. One of the synthetic polymers used as the base material for HFM is PSf. PSf has mechanical strength, heat resistance, and is easily formed into HFM. However, PSf has disadvantages such as lack of active side and less compatible with blood due to its hydrophobic properties. Modification using PEG and chitosan will reduce the hydrophobicity of the PSf. Membrane results were analyzed the physical, chemical, and transportability for urea and creatinine. The results of functional group characterization by FTIR show that the modification reaction was successfully carried out on polysulfone to produce PEG-PSf/CS. The modification succeeded in making the PSf membrane more hydrophilic, as evidenced by a decrease in the contact angle from 69.4° (PSf) to 53° (PEG-PSf/CS). Water uptake capability increases to 609%, and membrane porosity increases porosity increased from 72 to 83%. The water flux is also increased. Creatinine clearance ability increases from 0.09 mg/dl to 0.25 mg/dL. Urea clearance ability increases from 2.3 mg/dL to 3.07 mg/dL. The SEM image showed that the modification makes the membranes more porous.

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Section: Functional Groups Analysis Using Ftirmentioning

confidence: 97%

Section: Characterizationmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

“…Code of membranes a wavelength of 430 nm. The permeation of membrane is calculated using Equation (2)[ 15 ]:…”

mentioning

confidence: 99%

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