Chiral separation through a single substituent association

Enantioselective chromatography: Selection of chiral recognition models

“…If both energetically low but dominant complexes are formed the classical theory of chiral recognition would fail. This model is based on symmetry requirements (explained by analysis of appropriate distance matrices) and might provide new insights in the design of novel chiral resolving systems, but also provide support to the attempts to explain chiral recognition by one-point interactions [23]. The basic criterion for molecular recognition of chiral compounds is the inequality of the distance matrices of SO-SA complexes under ambient experimental conditions.…”

Enantioselective chromatography: Selection of chiral recognition models

“…If both energetically low but dominant complexes are formed the classical theory of chiral recognition would fail. This model is based on symmetry requirements (explained by analysis of appropriate distance matrices) and might provide new insights in the design of novel chiral resolving systems, but also provide support to the attempts to explain chiral recognition by one-point interactions [23]. The basic criterion for molecular recognition of chiral compounds is the inequality of the distance matrices of SO-SA complexes under ambient experimental conditions.…”

Enantioselective chromatography: Selection of chiral recognition models

“…If both energetically low but dominant complexes are formed the classical theory of chiral recognition would fail. This model is based on symmetry requirements (explained by analysis of appropriate distance matrices) and might provide new insights in the design of novel chiral resolving systems, but also provide support to the attempts to explain chiral recognition by one-point interactions [23]. The basic criterion for molecular recognition of chiral compounds is the inequality of the distance matrices of SO-SA complexes under ambient experimental conditions.…”

Enantioselective chromatography: Selection of chiral recognition models

“…If both energetically low but dominant complexes are formed the classical theory of chiral recognition would fail. This model is based on symmetry requirements (explained by analysis of appropriate distance matrices) and might provide new insights in the design of novel chiral resolving systems, but also provide support to the attempts to explain chiral recognition by one-point interactions [23]. The basic criterion for molecular recognition of chiral compounds is the inequality of the distance matrices of SO-SA complexes under ambient experimental conditions.…”