volume 51, issue 2, P276-276 2007
DOI: 10.1002/jctb.280510215
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Abstract: Fermentative anaerobic bacteria are particularly useful agents of bioreduction, although their use for this purpose has hitherto been rather haphazard. The ability of two such organisms to reduce a variety of prochiral ketones has been examined.The heterolaclic fermenter Lactobacillus brruis NCIB 947 displayed high specific activities of bioreduction but yielded products in low enantiomeric excess. This strain possessed several (NADPH-dependent) ketone reductases and one of these, when partially purified, sti…

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