Childhood discoid lupus erythematosus

George, Pierre M.

doi:10.1001/archderm.129.5.613

Cited by 28 publications

(21 citation statements)

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“…The skin lesions resolved without leaving scars but recurred chronically after sun exposure. In adults with LET, a slight male predominance is seen, and in this report, 2 of the 3 patients were boys, which is also common in children with DLE [7, 16]. Interestingly, photoprovocation tests, which had been performed in 2 of the patients, demonstrated no characteristic skin lesions after UV irradiation, although the patients had a positive history of photosensitivity.…”

Section: Discussionmentioning

confidence: 48%

“…The largest series of 8 patients with DLE, reported in 1993 by George and Tunnessen [7], showed that the clinical picture and the chronic course typical for the adult onset of the disease are also prominent in children. Two reports [9, 10]from other groups demonstrated DLE with a linear distribution.…”

Section: Discussionmentioning

confidence: 99%

“…Fewer than 20 cases of DLE have previously been reported in the literature [3, 4, 5, 6, 7, 8, 9, 10, 11], and not more than 2% of patients with this subtype develop skin lesions before the age of 10 years. The clinical morphologic features of childhood and adult DLE are comparable; however, childhood DLE has a male predominance, a low incidence of photosensitivity, and a high rate of progression to systemic manifestations compared with the adult form [7]. Although LET was first mentioned by Gougerot and Burnier in 1930 [12], it has rarely been documented in the literature.…”

Section: Introductionmentioning

confidence: 99%

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Lupus erythematosus tumidus in Childhood

Sonntag¹,

Lehmann²,

Megahed³

et al. 2003

Dermatology

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Lupus erythematosus (LE) is a rare disorder in childhood. Most patients reported in the literature present with systemic manifestations, and, to date, fewer than 20 children with chronic cutaneous LE have been documented. In this article, we describe 3 patients with childhood LE tumidus, an uncommon but distinct subtype of chronic cutaneous LE. The lesions are characterized by erythematous, urticaria-like, nonscarring plaques in sun-exposed areas and, unlike in other variants of chronic cutaneous LE, there is no epidermal involvement. The clinical, photobiological, and histologic features as well as the differential diagnoses of childhood LE tumidus are discussed and compared with the adult form of this disease.

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Section: Discussionmentioning

confidence: 48%

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Lupus erythematosus tumidus in Childhood

Sonntag¹,

Lehmann²,

Megahed³

et al. 2003

Dermatology

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“…Cutaneous lesions of LE with a linear dermatological pattern are rare [1,2,3,4,5,7,8,9,10,11,12,13,14,15,16]. To the best of our knowledge, only 4 cases of LEP with linear distribution have been reported in the literature [1,2,3,4].…”

Section: Discussionmentioning

confidence: 99%

Sclerodermic Linear Lupus Panniculitis: Report of Two Cases

Marzano¹,

Tanzi²,

Caputo³

et al. 2005

Dermatology

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Lupus erythematosus panniculitis is a rare disease characterized by deep subcutaneous nodules, most commonly localized on the upper limbs and face. Unique clinical presentations, such as linear configuration or ‘overlap’ forms between lupus erythematosus panniculitis and localized scleroderma have been reported. We present here the clinical characteristics, course and laboratory findings of 2 patients having linear lupus erythematosus panniculitis with localized scleroderma-like changes. The 2 patients (of the 14 patients with lupus erythematosus panniculitis seen by us since 1990) were females with a young age at the onset of disease (median, 25 years). In 1 case, evolution into systemic lupus erythematosus with severe renal involvement occurred whereas the other patient, who had a spontaneous abortion and exhibited anticardiolipin antibodies, should be followed and screened for the emergence of antiphospholipid syndrome. Thus, the clinical behavior of this variant seems to be more aggressive, as compared with the usual course of lupus erythematosus panniculitis, which is considered to be a benign disease, although some reports have suggested that its prognosis is not always favorable. The linear distribution could be the clinical hallmark of such a unique, ‘sclerodermic’ subset of lupus erythematosus panniculitis.

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“…According to literature, the incidence of this disorder in children is <2%. [34] As in adults, childhood DLE is associated with active inflammatory lesions (erythema, edema, telangiectasia), scaling with follicular plugging and atrophy. Itching, burning, and tenderness are usually the main symptoms.…”

Section: Discussionmentioning

confidence: 99%