Child with serogroup W135 primary meningococcal septic arthritis

Fidder, AR; Hartog, B. de; Faber, Tina E

doi:10.1136/bcr-2019-229510

Cited by 7 publications

(3 citation statements)

References 24 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Although most cases are due to serogroup B in our country, an increase in the number of cases caused by serogroup W 11 has been reported in Chile and Argentina. Also, cases of serogroup W have increased in Europe, which has led to adjustments in vaccination programs 16 . We found only two previous reports of PMA caused by this serogroup in PubMed; however, this was the most frequent serogroup in a series of nine cases in Argentina 3,16,17 .…”

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Primary meningococcal arthritis of the hip due to serogroup W in a pediatric patient

Dapueto¹,

Barrios²,

Zabala³

et al. 2021

BMHIM

View full text Add to dashboard Cite

Background: Primary meningococcal arthritis (PMA) is defined as the presence of acute septic arthritis with the identification of Neisseria meningitidis in synovial fluid or blood cultures but no clinical evidence of sepsis or meningitis. This report aimed to describe a clinical case of PMA caused by serogroup W, an uncommon etiology of this disease in Uruguay, and review the available literature. Case report: We report the case of a 5-year-old female, with no past medical history, admitted to the emergency department with a 12-hour history of fever of 39 °C and a limp. The patient was hemodynamically stable and had no clinical evidence of meningitis. Hip ultrasound showed an increase in synovial fluid. Arthrocentesis showed purulent exudate and synovial fluid culture showed no growth after five days. The blood culture showed isolates of N. meningitidis, serogroup W. The patient received treatment with ceftriaxone, and drainage of the affected joint was performed with excellent clinical response. Conclusions: Primary meningococcal arthritis is a rare presentation of meningococcal disease. Systematic arthrocentesis and the adequacy of antibiotic therapy when septic arthritis is clinically suspected are essential for confirming the diagnosis and decompressive drainage of the involved joint. This report is the first of PMA caused by serogroup W in Uruguay. Although the most common serogroup involved in meningococcal arthritis is serogroup B in Uruguay, an increase in serogroup W-related diseases has been reported in Chile and Argentina, emphasizing the need for epidemiological surveillance.

show abstract

Section: Discussionmentioning

confidence: 99%

“…Also, cases of serogroup W have increased in Europe, which has led to adjustments in vaccination programs 16 . We found only two previous reports of PMA caused by this serogroup in PubMed; however, this was the most frequent serogroup in a series of nine cases in Argentina 3,16,17 .…”

Section: Discussionmentioning

confidence: 99%

Primary meningococcal arthritis of the hip due to serogroup W in a pediatric patient

Dapueto¹,

Barrios²,

Zabala³

et al. 2021

BMHIM

View full text Add to dashboard Cite

show abstract

“…2; citations provided in Supplementary Table S2). Among the 25 reported cases of septic arthritis, 60.9% were infected with serogroup W [19,[21][22][23][24][25]. Additionally, three patients (13.0%) had septic arthritis due to serogroup Y [26,27].…”

Section: Clinical Presentationmentioning

confidence: 99%

The Diverse Spectrum of Invasive Meningococcal Disease in Pediatric and Adolescent Patients: Narrative Review of Cases and Case Series

Bobde,

Sohn,

Bekkat-Berkani

et al. 2024

Infect Dis Ther

View full text Add to dashboard Cite

Introduction: Invasive meningococcal disease (IMD) is a potentially life-threatening disease caused by Neisseria meningitidis infection. We reviewed case reports of IMD from newborns, infants, children, and adolescents, and described the real-life clinical presentations, diagnoses, treatment paradigms, and clinical outcomes.Methods: PubMed and Embase were searched for IMD case reports on patients aged B 19 years published from January 2011 to March 2023 (search terms ''Neisseria meningitidis'' or ''invasive meningococcal disease '', and ''infant'', ''children'', ''paediatric'', pediatric'', or ''adolescent''). Results: We identified 97 publications reporting 184 cases of IMD, including 25 cases with a fatal outcome. Most cases were in adolescents aged 13-19 years (34.2%), followed by children aged 1-5 years (27.6%), children aged 6-12 years (17.1%), infants aged 1-12 months (17.1%), and neonates (3.9%). The most common disease-causing serogroups were W (40.2%), B (31.7%), and C (10.4%). Serogroup W was the most common serogroup in adolescents (17.2%), and serogroup B was the most common in the other age groups, including children aged 1-5 years (11.5%). The most common clinical presentations were meningitis (46.6%) and sepsis (36.8%). Conclusions: IMD continues to pose a threat to the health of children and adolescents. While this review was limited to case reports and is not reflective of global epidemiology, adolescents represented the largest group with IMD. Additionally, nearly half of the patients who died were adolescents, emphasizing the importance of monitoring and vaccination in this age group. Different infecting serogroups were predominant in different age groups, highlighting the usefulness of multivalent vaccines to provide the broadest possible

show abstract

Primary septic arthritis of the knee caused by Neisseria meningitidis serogroup B in an elderly patient. Case report and review of the literature

et al. 2022

View full text Add to dashboard Cite

Purpose: Primary meningococcal arthritis (PMA) represents an uncommon clinical presentation of meningococcal infection, mainly reported among young people. Herein, a case of PMA of the knee in an elderly patient is described.Case presentation: On January 2022, an 87-year-old patient arrived at hospital with continuous fever persisting for three days and a picture of joint pain, swelling, redness, and warmth of her left knee. An arthrocentesis was promptly performed and the inoculated synovial uid turned positive with numerous Gram-negative diplococci at the microscopic examination. The BioFire® FilmArray®Meningitis/Encephalitis (ME) Panel (bioMérieux) quickly con rmed the presence of Neisseria meningitidis. The meningococcal isolate belonged to the serogroup B (MenB), Sequence type (ST)-162/ clonal complex (cc)162.Two grams of ceftriaxone twice a day were administered for 21 days; than cefditoren pivoxil 400 mg twice a day for further 6 weeks after discharge.

show abstract

Child with serogroup W135 primary meningococcal septic arthritis

Cited by 7 publications

References 24 publications

Primary meningococcal arthritis of the hip due to serogroup W in a pediatric patient

Primary meningococcal arthritis of the hip due to serogroup W in a pediatric patient

The Diverse Spectrum of Invasive Meningococcal Disease in Pediatric and Adolescent Patients: Narrative Review of Cases and Case Series

Primary septic arthritis of the knee caused by Neisseria meningitidis serogroup B in an elderly patient. Case report and review of the literature

Contact Info

Product

Resources

About