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“…Under gradient conditions, the chemotactic index (C.I.) was calculated by dividing directional distance (net distance towards source) by total distance (13). By this method, a cell moving directly towards the source will exhibit a C.I.…”
Section: Cyclic Amp Reduces Motility Under Nongradient Conditionsmentioning
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“…Under gradient conditions, the chemotactic index (C.I.) was calculated by dividing directional distance (net distance towards source) by total distance (13). By this method, a cell moving directly towards the source will exhibit a C.I.…”
Section: Cyclic Amp Reduces Motility Under Nongradient Conditionsmentioning
“…Most investigations are not specifically designed to discriminate between orientation, attraction, or accumulation and how they are induced. For example, some commonly applied "chemotactic indices" compare relative path lengths (61), population shifts (55), or angles ofapproach (3), which are not specific features of taxis. Furthermore, effectively identical klinokinesis mechanisms have been advanced to explain bacterial attraction (18,19) and chemotaxis in leukocytes and Dictyostelium.…”
Section: Concepts Of Cell Behaviormentioning
“…Perhaps ameboid movement is paralyzed by inhibition of the proteolytic enzymes of the cells. It may be simply a case of negative chemotaxis (2).…”
Section: Time In Hoursmentioning
“…This phenomenon is believed to result from the liberation of chemotactic substances by the injured ceUs. The only chemotactic substances which have actually been obtained from injured tissues are polypeptides (2)(3)(4)(5)(6)(7)(8). To date no evidence has been found to show that the products of fat or carbohydrate breakdown are the active chemotactic factors in injured tissues for polymorphonudear leukocytes (8).…”
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