2003
DOI: 10.1001/archopht.121.10.1513-a
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Chemoreduction for Retinoblastoma

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“…In the 1970s, enucleation as a life-saving modality was key to improved prognosis. Not only did CRD with consolidation treatment of thermotherapy, cryotherapy, and plaque radiotherapy control intraocular retinoblastoma and improve globe salvage, often with vision preservation, it was soon realized that this systemic therapy provided reduced risk for pinealoblastoma and second cancers [33,34,35 && ]. In the 1990s, the chemoreduction (CRD) era was heralded [18][19][20][21][22][23][24][25][26][27][28][29][30][31][32].…”
Section: Chemotherapy For Retinoblastoma
mentioning
confidence: 99%
“…. Others argued that this finding was related to the lack of EBRT [34]. been a deterrent to the widespread use of chemotherapy for patients with retinoblastoma'.…”
Section: The Era Of Intravenous Chemotherapy (Chemoreduction)
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confidence: 99%
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