ChemInform Abstract: γ‐Substituted Bis(pivaloyloxymethyl)ester Analogues of Fosmidomycin and FR900098.

Abstract

Antibiotics U 1200 γ-Substituted Bis(pivaloyloxymethyl)ester Analogues of Fosmidomycin and FR900098. -The in vitro antimalarial activity of title compounds (VIII) is investigated. However, the γ-substituted analogues display only weak to moderate efects against the chloroquine-sensitive strain 3D7 of Plasmodium falciparum. -(KURZ*, T.; BEHRENDT, C.; PEIN, M.; KAULA, U.; BERGMANN, B.; WALTER, R. D.; Arch.