ChemInform Abstract: Ternary Condensation of Biginelli Thiones, Chloroacetic Acid, and Aldehydes as an Effective Approach Towards Thiazolo[3,2‐a]pyrimidines and 5‐Arylidenethiazolidine‐2,4‐diones.

Abstract

Ternary Condensation of Biginelli Thiones, Chloroacetic Acid, and Aldehydes as an Effective Approach Towards Thiazolo[3,2-a]pyrimidines and 5-Arylidenethiazolidine-2,4-diones. -The three-component reaction of thiones (I) with aldehydes (II) and chloroacetic acid readily affords thiazolo[3,2-a]pyrimidines (IV), whilst prolonged reaction times leads to the formation of hydrolysis products (V). -(LEBEDYEVA*, I. O.; POVSTYANOY, M. V.; RYABITSKII, A. B.; POVSTYANOY, V. M.; J.