volume 30, issue 43, Pno-no 2010
DOI: 10.1002/chin.199943032
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Michael H. Wu, Karl B. Hansen, Eric N. Jacobsen

Abstract: 1999 stereochemistry stereochemistry (general, optical resolution) O 0030 -032Regio-and Enantioselective Cyclization of Epoxy Alcohols Catalyzed by a [Co III (salen)] Complex.-Reaction of epoxy alcohols in the presence of a Co(III)-salen complex proceeds with excellent asymmetric induction to furnish novel cyclic and bicyclic ethers (up to seven-membered rings) in high optical purity. The method can be used for the kinetic resolution of racemic epoxy alcohols (I) as well as for the desymmetrization of meso su…

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