volume 30, issue 42, Pno-no 2010
DOI: 10.1002/chin.199942262
View full text
Sign up to set email alerts
P. R. Blakemore,
P. Grzywacz,
P. J. Kocienski
et al.

Abstract: On the Julia Alkenylation Reaction in Vitamin D Synthesis. Isolation of Four Geometrical Isomers of Vitamin D 4 .-Reinvestigation of the coupling of sulfone (II) with aldehyde (III) using the Julia alkenylation procedure indicates that vitamin D 4 (IV) and its geometric isomers (V)-(VII) are formed in a 75:10:10:5 ratio, respectively. The building blocks (II) and (III) are prepared from vitamin D 2 (I). -(BLAKEMORE, P. R.; GRZYWACZ, P.; KOCIENSKI, P. J.; MARCZAK, S.; WICHA, J.; Pol.