volume 30, issue 43, Pno-no 2010
DOI: 10.1002/chin.199943170
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Alain Krief,
Laurent Provins,
Willy Dumont

Abstract: Metal-Mediated, Completely Diastereofacial Conjugate Addition of Trialkylstannylmetal Reagents to γ-Alkoxy-α,β-Unsaturated Esters.-The synthesis of β-stannyl esters (III) and (V) can be achieved in a diastereospecific manner from the title unsaturated esters (I) and (VI) by properly choosing the trialkyltin reagent to be added. Thus, trialkylstannyllithium reagents (II) add exclusively to the si-face of the (Z)-ene esters (I) providing β-stannylesters (III), while addition to the corresponding (E)-ene ester (…

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