ChemInform Abstract: Doped Nano‐Sized Copper(I) Oxide (Cu<sub>2</sub>O) on Melamine—Formaldehyde Resin: A Highly Efficient Heterogeneous Nano Catalyst for “Click” Synthesis of Some Novel 1H‐1,2,3‐Triazole Derivatives Having Antibacterial Activity.

Rad, Mohammad Navid Soltani; Behrouz, Somayeh; Movahedian, Abdollah; Doroodmand, Mohammad Mahdi; Ghasemi, Younes; Rasoul‐Amini, Sara; Gandomani, Abdol‐Rasoul Ahmadi; Rezaie, Ramin

doi:10.1002/chin.201335129

Cited by 2 publications

(2 citation statements)

References 1 publication

Supporting

Mentioning

Contrasting

Order By: Relevance

“…In order to solve the problem, different heterogeneous copper catalysts have been introduced for the preparation of 1,2,3-triazoles. Examples of heterogeneous copper catalysts used for the click reaction include silica-supported nanocopper, magnetite-supported copper nanoparticles, − polymer-supported copper catalysts, polyvinylpyrrolidone-coated copper nanoparticles, , Cu/C, − surfactant-assisted hydrothermal-synthesized Cu nanoparticles, hetero-bimetallic Cu–Ni/C, CuO, , Cu(II)-anchored functionalized mesoporous, and melamine-formaldehyde resin-supported copper nanoparticles. Even with simple handling of the heterogeneous catalysts, they are typically less effective than their homogeneous counterparts.…”

Section: Introductionmentioning

confidence: 99%

Copper Nanoparticles Supported on Agarose as a Bioorganic and Degradable Polymer for Multicomponent Click Synthesis of 1,2,3-Triazoles under Low Copper Loading in Water

Jeddi

2014

ACS Sustainable Chem. Eng.

View full text Add to dashboard Cite

Agarose-supported copper nanoparticles (CuNPs@agarose) were prepared by immobilization of copper bromide on agarose followed by in situ chemical reduction. The new material was characterized by SEM, EDX, TEM, TGA, XRD, nitrogen adsorption–desorption, and solid UV–vis analysis. The catalytic activity of CuNPs@agarose was assessed in the three component click synthesis of 1,2,3-triazoles in water under low catalyst loading and mild reaction conditions. The easy synthesis and air-stable catalyst was recycled for five runs with small drops in catalytic activity.

show abstract

Section: Introductionmentioning

confidence: 99%

Copper Nanoparticles Supported on Agarose as a Bioorganic and Degradable Polymer for Multicomponent Click Synthesis of 1,2,3-Triazoles under Low Copper Loading in Water

Jeddi

2014

ACS Sustainable Chem. Eng.

View full text Add to dashboard Cite

show abstract

“…In continuation of our ongoing research on the preparation of heterogeneous nanoCu catalystsand their application in organic transformation [16] [21],hereby, we have explainedt he preparation and characterization of Cu/aminoclay/reduced graphene oxide nanohybrid (Cu/AC/r-GO nanohybrid)a sh ighly efficient novel nanohybrid catalyst for the very mild synthesis of some 1H-1,2,3-triazolyl carboacyclic nucleosides via a Click Huisgen cycloaddition of N-propargyl nucleobases and azido alcohols in THF/H 2 Oa troom temperature (Scheme).…”

mentioning

confidence: 97%

Copper/Graphene/Clay Nanohybrid: A Highly Efficient Heterogeneous Nanocatalyst for the Synthesis of Novel 1,2,3‐Triazolyl Carboacyclic Nucleosides via ‘Click’ Huisgen 1,3‐Dipolar Cycloaddition

Rad

Behrouz

Hoseini

et al. 2015

Helvetica Chimica Acta

Self Cite

View full text Add to dashboard Cite

Avery mild and highly efficient synthesis of somenovel 1H-1,2,3-triazolylcarboacyclic nucleosides via aClick Huisgen cycloaddition of N-propargyl nucleobasesand azido alcohols using Cu/aminoclay/ reduced grapheneo xide nanohybrid (Cu/AC/r-GO nanohybrid)a sn anocatalyst is described.T he preparation and characterization of Cu/AC/r-GO nanohybrid are discussed.T his catalyst was characterized by X-ray diffraction, FT-IR, TEM, and energy-dispersive analysiso fX -ray techniques. Cu/AC/r-GO nanohybrid is as table and highly efficient heterogeneousn anocatalyst that can be easily prepared, used,a nd restoredf rom the reaction mixtureb ys imple filtration, and reused for many consecutivet rials without significant decrease in activity.Introduction. -D rug design and synthesis based on non-natural nucleosides are prominence strategies to overcomem iscellaneous infections and diseases caused by viruses,bacteria, cancer, etc.[1].Threemain strategiesare normally applied on natural nucleosides to access agreat deal of diverse non-natural nucleosides,encompassing i) modification of functionalities on nucleobases and/or replacement of nucleobases with their similar heterocyclic analogs or isosteres; ii)a lteration of the sugar residues backbone,a nd finally iii)c onversion, as well as conjugationo ff ree OH groups to various functionalities [2].Inconnection with the first strategy,itiswell demonstrated and fully established that the replacement of purine and pyrimidine nucleobases in natural nucleosides with those of azole derivatives not only doesnt abolish the biological activity,b ut also endows the leading properties [3]. This inspiration in nucleobase change has been emergedi nt he design and synthesis of well-established non-natural nucleosides, i.e.,ribavirin (virazole), mizoribine (bredinin), pyrazofurine, and tert-butyldimethylsilylspiroaminooxathioledioxide (TSAO),w hich exhibit antiviral, antitumor, and immunosuppressive activities (Fig. 1)[ 4].Since the discovery of zidovudine (AZT; Fig. 1)a sp otent anti-HIV drug [5], enormous efforts were conducted to conjugatethe AZT scaffoldwith various naturally occurring molecules or drugs [6]. In this regard,t he Huisgen azideÀalkyne cycloaddition was found to be ah ighly efficient and reliable tool for tetheringA ZT to diverse molecules [6]. This became the starting point for extensive endeavors to incorporate 1H-1,2,3-triazolyl cores intothe nucleosideframework [7]. In general, the Helv eticaChimica Acta -V ol. 98 (2015) 1210 2015 Verlag Helvetica Chimica Acta AG,Z ürich incorporation of the 1H-1,2,3-triazolylgroupinto amolecularscaffold is an interesting task, since the 1H-1,2,3-triazolyl moiety involvesr emarkable biological activities,a s well as recognition by enzymes and receptors in the cell [8]. Moreover, 1H-1,2,3-triazolyl cores are knowna st he non-classical isostere of amideb ecause of having considerable topological and electronic similarities.Given the biological importanceof 1H-1,2,3-triazolyl cores,t hey have been extensively used in the design of new nucleos...

show abstract

ChemInform Abstract: Doped Nano‐Sized Copper(I) Oxide (Cu₂O) on Melamine—Formaldehyde Resin: A Highly Efficient Heterogeneous Nano Catalyst for “Click” Synthesis of Some Novel 1H‐1,2,3‐Triazole Derivatives Having Antibacterial Activity.

Cited by 2 publications

References 1 publication

Copper Nanoparticles Supported on Agarose as a Bioorganic and Degradable Polymer for Multicomponent Click Synthesis of 1,2,3-Triazoles under Low Copper Loading in Water

Copper Nanoparticles Supported on Agarose as a Bioorganic and Degradable Polymer for Multicomponent Click Synthesis of 1,2,3-Triazoles under Low Copper Loading in Water

Copper/Graphene/Clay Nanohybrid: A Highly Efficient Heterogeneous Nanocatalyst for the Synthesis of Novel 1,2,3‐Triazolyl Carboacyclic Nucleosides via ‘Click’ Huisgen 1,3‐Dipolar Cycloaddition

Contact Info

Product

Resources

About

ChemInform Abstract: Doped Nano‐Sized Copper(I) Oxide (Cu2O) on Melamine—Formaldehyde Resin: A Highly Efficient Heterogeneous Nano Catalyst for “Click” Synthesis of Some Novel 1H‐1,2,3‐Triazole Derivatives Having Antibacterial Activity.

Cited by 2 publications

References 1 publication

Copper Nanoparticles Supported on Agarose as a Bioorganic and Degradable Polymer for Multicomponent Click Synthesis of 1,2,3-Triazoles under Low Copper Loading in Water

Copper Nanoparticles Supported on Agarose as a Bioorganic and Degradable Polymer for Multicomponent Click Synthesis of 1,2,3-Triazoles under Low Copper Loading in Water

Copper/Graphene/Clay Nanohybrid: A Highly Efficient Heterogeneous Nanocatalyst for the Synthesis of Novel 1,2,3‐Triazolyl Carboacyclic Nucleosides via ‘Click’ Huisgen 1,3‐Dipolar Cycloaddition

Contact Info

Product

Resources

About

ChemInform Abstract: Doped Nano‐Sized Copper(I) Oxide (Cu₂O) on Melamine—Formaldehyde Resin: A Highly Efficient Heterogeneous Nano Catalyst for “Click” Synthesis of Some Novel 1H‐1,2,3‐Triazole Derivatives Having Antibacterial Activity.