2010
DOI: 10.1002/chin.199942209 View full text |Buy / Rent full text
|
|
Christopher J. Moody,
Peter T. Gallagher,
Andrew P. Lightfoot
et al.

Abstract: Chiral Oxime Ethers in Asymmetric Synthesis. Part 3. Asymmetric Synthesis of (R)-N-Protected α-Amino Acids by the Addition of Organometallic Reagents to the ROPHy Oxime of Cinnamaldehyde.-The new route to α-amino acids (VIII) is based on the highly diastereoselective addition of organolithium reagents to (I), which is easily obtained from cinnamaldehyde and (R)-O-(1-phenylbutyl)hydroxylamine in good yield. The method can be extended to the synthesis of quaternary amino acids, e.g. (XII), using ketoxime ethers … Show more

Help me understand this report

Search citation statements

Order By: Relevance
0
0
0
0
0
0
1
0

Publication Types

Select...

Relationship

0
0

Authors

Journals