volume 30, issue 44, Pno-no 2010
DOI: 10.1002/chin.199944057
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Chris A. Tarling, Andrew B. Holmes, Roger E. Markwell, Neil D. Pearson

Abstract: ring closure reactions ring closure reactions O 0130 44 -057 β-, γ-, and δ-Lactams as Conformational Constraints in Ring-Closing Metathesis. -Ring-closing metathesis of bis(alkenyl)-substituted lactams in the presence of Grubbs catalyst affords the corresponding lactam-fused 6-, 7-, or 8-membered azacycles (II) (9 examples) in high yields. -(TARLING, CHRIS A.; HOLMES, ANDREW B.; MARKWELL, ROGER E.; PEARSON, NEIL D.; J.