volume 30, issue 42, Pno-no 2010
DOI: 10.1002/chin.199942159
View full text
Kamajit Singh, Prasant K. Deb

Abstract: A Versatile Approach to trans-1,3-Disubstituted Tetrahydro-βcarbolines Using Oxazinanes.-The reaction of the L-tryptophan derivatives (I) with the oxazines (II) represents a variant of the classical Pictet-Spengler reaction. It proceeds thermodynamically controlled to yield the trans 1,3-disubstituted tetrahydro-β-carbolines (III) predominantly.-(SINGH, KAMAJIT; DEB, PRASANT K.; Heterocycles 51 (1999) 7, 1509-1512; Dep. Appl. Chem. Sci. Technol., Guru Nanak Dev Univ., Amritsar 143 005, India; EN)