Thomas Billert, Rainer Beckert, Peer Fehlinget al.
A New Domino Reaction Based on [4 + 2]-Cycloadditions of Pyrido[1,2-a]pyrazines with Azadienophiles.-The reaction of pyridopyrazines (I) with nitroso compounds (II) provides triazinones (III) via domino reaction involving a cycloaddition and a ring transformation reaction step. Diazene derivatives such as (IV) and azodicarboxylates (VI) and (VIII) react with (I) to give triazine derivatives (V), (VII), and (IX), respectively. The oxygen adduct (X) is formed on standing pyrazine (Ia) for several weeks in methy…
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