volume 30, issue 43, Pno-no 2010
DOI: 10.1002/chin.199943189
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Alvaro B. Onofrio, Antonio C. Joussef, Faruk Nome

Abstract: A Convenient Synthesis of Optically Active N-(o-Carboxybenzoyl)-L-amino Acids.-Modified procedures are given for the synthesis of compounds (V) and (VI) in high optical purities. Compounds of type (VI) can also be prepared by reacting (I) with phthalic anhydride (IV). The compounds are useful as simple models of aspartic proteinases [for intermediates (III) no yields given]. -(ONOFRIO, ALVARO B.; JOUSSEF, ANTONIO C.; NOME, FARUK; Synth. Commun. 29 (1999) 17, 3039-3049; Dep. Quim., Univ. Fed.