volume 30, issue 43, Pno-no 2010
DOI: 10.1002/chin.199943125
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T. K. Vinh, M. Ahmadi, P. O. Lopez Delgado, S. Fernandez Perez, H. M. Walters, H. J. Smith, P. J. Nicholls, C. Simons

Abstract: 1-[(Benzofuran-2-yl)phenylmethyl]-triazoles and -tetrazoles. PotentCompetitive Inhibitors of Aromatase.-The synthesized triazoles (VIa), (VIb) show greater inhibition of human placental aromatase than tetrazoles (VIc), (VId). It is also shown that desired activity can be increased by phenyl substitution but decreased by benzofuran modifications. -(VINH, T. K.; AHMADI, M.; LOPEZ DELGADO, P. O.; FERNANDEZ PEREZ, S.; WALTERS, H. M.; SMITH, H. J.; NICHOLLS, P. J.; SIMONS, C.; Bioorg.