volume 30, issue 43, Pno-no 2010
DOI: 10.1002/chin.199943099
View full text
|
|
Share
G. Wurm, S. Schwandt

Abstract: 1999quinones quinones (naphthalene compounds) Q 0910 -0991,4-Naphthoquinones. Part 27. 2-(3-Halogen-4-hydroxyphenyl)-1,4naphthoquinones from Their 2-(3,5-Di-tert-butyl-4-hydroxyphenyl) Congeners, Potent 5-Lipoxygenase Inhibitors.-A new and simple method for the synthesis of halogenated hydroxyphenyl-naphthoquinones based on a debutylation/halogenation reaction is described. Selected compounds are evaluated for their 5-lipoxygenase (5-LOX) inhibiting and antioxidative properties. Quinone (III) and benzofuran (…

expand abstract