ChemInform Abstract: 1,3‐Thiazepines. Part 4. Reaction of 2‐Iminothiazepines with Methyl Acrylate. Crystal and Molecular Structure of 2‐Phenylimino‐3‐(β‐ methoxycarbonylethyl)‐ and 2‐Benzyliminohexahydro‐1,3‐thiazepines.

Abstract

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.

Molecular and crystal structure characteristics of 2-phenylaminotetrahydro-1,3-thiazepine hydrochloride and 2-phenyliminohexahydro-1,3-thiazepine

“…1,3-Thiazepines are studied less than their fiveor six-membered analogs. A series of hydrogenated 1,3thiazepine derivatives have been obtained by Ambartsumova et al [7][8][9][10]], including 2-benzyliminohexahydro-1,3-thiazepine (imine form), which was reported as an amine form (2-benzyl aminotetrahydro-1,3-thiazepine) by Olszenko-Piontkowa and Urbanski [11]. The single-crystal X-ray diffraction method plays an important role to attribute a reaction product to an imine form [8].…”

“…A series of hydrogenated 1,3thiazepine derivatives have been obtained by Ambartsumova et al [7][8][9][10]], including 2-benzyliminohexahydro-1,3-thiazepine (imine form), which was reported as an amine form (2-benzyl aminotetrahydro-1,3-thiazepine) by Olszenko-Piontkowa and Urbanski [11]. The single-crystal X-ray diffraction method plays an important role to attribute a reaction product to an imine form [8]. Furthermore, the spatial arrangement of the atoms and the conformation of the seven-membered ring, which was obtained by X-ray diffraction analysis [8] or theoretical methods [12], is of great importance for amine-imine tautomeric chemistry.…”

“…The single-crystal X-ray diffraction method plays an important role to attribute a reaction product to an imine form [8]. Furthermore, the spatial arrangement of the atoms and the conformation of the seven-membered ring, which was obtained by X-ray diffraction analysis [8] or theoretical methods [12], is of great importance for amine-imine tautomeric chemistry. But only a few compounds that include the 1,3-thiazepine ring containing (with Refcodes in CCDC [13]: BEVNEW [14], BEVNIA [14], JEPYOS [15], QIBMET [16], QIBMET01, QIBMET02, QIBMET03, QIBMET04 [17], QOZMUO [18], RENVOV [8], RENVIP [8], and YUKPIE [19]) were characterized by the single-crystal XRD method.…”