Chemical compositional analysis of the Tamarix hispida aerial part extract obtained in ethanol solutions of different concentration

Iskhanov, Yerbol

doi:10.5937/jaes16-17333

Cited by 2 publications

(4 citation statements)

References 26 publications

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“… Identification Molecular formula Exact mass R t (min) m/z MS/MS fragments Ref. (+ ve) (+ ve) 1 Methyl gallate C 8 H 8 O 5 184.0371 0.64 184.9999 125.9427-141.9137 [ 52 ] 2 Morphinan-4,6-diol, N-formyl-6-acetate(ester) C 19 H 23 NO 4 329.16271 2.31 330.1706 260.1651 [ 53 ] 3 1,6-Di- O -galloyl- d -glucose (nilocitin) C 20 H 20 O 14 484.0853 2.42 485.0025 171.0516-315.0885- 333.0927 [ 30 , 54 ] 4 Hispidulin C 16 H 12 O 6 300.06339 7.08 300.9978 287.0618, 271.0781 [ 55 ] 5 Methyl gallate methyl ether C 9 H 10 O 5 198.05282 7.53 199.0607 183.2035, 182.1017, 168.1108, 167.1539 [ …”

Section: Resultsmentioning

confidence: 99%

Chemical profiling and cytotoxic potential of the n-butanol fraction of Tamarix nilotica flowers

Fayed

Bakr

Yosri

et al. 2023

BMC Complement Med Ther

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Background Cancer represents one of the biggest healthcare issues confronting humans and one of the big challenges for scientists in trials to dig into our nature for new remedies or to develop old ones with fewer side effects. Halophytes are widely distributed worldwide in areas of harsh conditions in dunes, and inland deserts, where, to cope with those conditions they synthesize important secondary metabolites highly valued in the medical field. Several Tamarix species are halophytic including T.nilotica which is native to Egypt, with a long history in its tradition, found in its papyri and in folk medicine to treat various ailments. Methods LC–LTQ–MS–MS analysis and 1H-NMR were used to identify the main phytoconstituents in the n- butanol fraction of T.nilotica flowers. The extract was tested in vitro for its cytotoxic effect against breast (MCF-7) and liver cell carcinoma (Huh-7) using SRB assay. Results T.nilotica n-butanol fraction of the flowers was found to be rich in phenolic content, where, LC–LTQ–MS–MS allowed the tentative identification of thirty-nine metabolites, based on the exact mass, the observed spectra fragmentation patterns, and the literature data, varying between tannins, phenolic acids, and flavonoids. 1H-NMR confirmed the classes tentatively identified. The in-vitro evaluation of the n-butanol fraction showed lower activity on MCF-7 cell lines with IC50 > 100 µg/mL, while the higher promising effect was against Huh-7 cell lines with an IC50= 37 µg/mL. Conclusion Our study suggested that T.nilotica flowers' n-butanol fraction is representing a promising cytotoxic candidate against liver cell carcinoma having potential phytoconstituents with variable targets and signaling pathways.

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Section: Resultsmentioning

confidence: 99%

Chemical profiling and cytotoxic potential of the n-butanol fraction of Tamarix nilotica flowers

Fayed

Bakr

Yosri

et al. 2023

BMC Complement Med Ther

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“…This plant contains biologically active substances polyphenols, terpenoids, and a complex of steroids. It has been proven that extracts and individual components have antimicrobial, antifungal, antiamnestics, cytotoxic, and antioxidant properties and are active as hemostatic agents, as well as against diabetes mellitus [15][16][17][18].…”

Section: Introductionmentioning

confidence: 99%

“…In different papers [15][16][17][18], it was found that the Tamarix hispida plant has high antioxidant properties in vitro due to the presence of terpenoid compounds in its composition [8]. In addition, the qualitative and quantitative component composition of the Tamarix hispida plant has been studied.…”

Section: Introductionmentioning

confidence: 99%

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Study of the Mechanical Properties of Gelatin Films with Natural Compounds of Tamarix hispida

Zhumagaliyeva,

Abdikarim,

Berikova

et al. 2023

Eurasian Chem.-Technol. J.

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In this work, an extract of the Tamarix hispida (TH-10) was prepared in 10 vol.% water-ethanol solution. Based on the properties of antioxidant, and anti-inflammatory activity, various gelatin films containing (10–15 wt.%) gelatin were obtained. The fabricated gelatin films containing TH-10 extract were used as wound dressings for burns. Their deformation properties, physical and mechanical properties, and SEM micrographs were defined. An additional film structure was determined by using a Fourier transform infrared spectrometer (FT-IR). The strength of polymer films containing TH-10 depends on gelatin content. This indicates that the gelatin film binds the TH-10 with the help of hydrophobic interactions. It was found that the higher amount of gelatin leads to lower tear resistance of films. This is due to the formation of micro-cracks on the surface of films leading to their easy rupture. During the study of tensile strength, it was proven that the optimal amount of glycerin in the film is 5 vol.%. The polymer film containing 12 wt.% gelatin and 1 wt.% TH-10 was recognized as the most effective composition in terms of strength and elasticity properties for application as wound dressing materials.

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Chemical compositional analysis of the Tamarix hispida aerial part extract obtained in ethanol solutions of different concentration

Abstract: In this article, extracts from aerial part of Tamarix hispida Wild harvested in 2016 in the Ile example,

Cited by 2 publications

References 26 publications

Chemical profiling and cytotoxic potential of the n-butanol fraction of Tamarix nilotica flowers

Chemical profiling and cytotoxic potential of the n-butanol fraction of Tamarix nilotica flowers

Study of the Mechanical Properties of Gelatin Films with Natural Compounds of Tamarix hispida

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