2012
DOI: 10.1590/s0102-695x2012005000034
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Chemical composition of hydroethanolic extracts from Siparuna guianensis, medicinal plant used as anxiolytics in Amazon region

Abstract: Siparuna guianensis Aubl., Siparunaceae, is used as anxiolytic plants in folk medicine by South-American indians, "caboclos" and river-dwellers. This work focused the evaluation of phenolic composition of hydroethanolic extract of S. guianensis through HPLC-DAD-ESI/MS/MS. The constituents exhibited protonated, deprotonated and sodiated molecules and the MS/MS fragmentation of protonated, deprotonated and sodiated molecules provided product ions with rich structural information. Vicenin-2 (apigenin-6,8-di-C-glu… Show more

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Cited by 31 publications
(39 citation statements)
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“…Comparing with MS literature data (Piccinelli et al, 2008), this compound was characterized as 6,8-di-C-glucosylapigenin, also known as vicenin-2. No commercial standard of vicenin-2 are available, therefore, this peak was compared with vicenin-2, present in P. incarnata extract, used as a surrogate standard (Negri et al, 2012).…”
Section: Passiflora Sidifoliamentioning
confidence: 99%
See 1 more Smart Citation
“…Comparing with MS literature data (Piccinelli et al, 2008), this compound was characterized as 6,8-di-C-glucosylapigenin, also known as vicenin-2. No commercial standard of vicenin-2 are available, therefore, this peak was compared with vicenin-2, present in P. incarnata extract, used as a surrogate standard (Negri et al, 2012).…”
Section: Passiflora Sidifoliamentioning
confidence: 99%
“…Its MS/MS data in negative ion mode are presented in Table 1. Vitexin is a one of the main constituent of some Passiflora species (Grundmann et al, 2008;Negri et al, 2012).…”
Section: Passiflora Sidifoliamentioning
confidence: 99%
“…The four flavones (peaks 1, 2, 3 and 4 in Fig. 2) were identified as orientin, isoorientin, vitexin-2"-O-rhamnoside and isovitexin-2"-O-rhamnoside, respectively, by comparing the maximal UV wavelength, mass values of the [M + H] + and [M -H] -ion, as well as the fragmentation pathways in previous literature (Ying et al, 2007;Abad-García et al, 2008;Negri et al, 2012;Yao et al, 2012;Sun et al, 2013). The ESI-MS spectra of peaks observed at 18.55 min (compound 1) and 18.91 min (compound 2) (Table 2, Fig.…”
Section: Characterisation Of Flavones C-glycosidesmentioning
confidence: 99%
“…The ethanolic leaf extract is used in injuries and as an anti-inflammatory agent (Montanari, 2010). The tea, in turn, is considered an abortifacient, febrifuge and stimulant (Montanari, 2010), and it is used as a flavoring because of its anxiolytic potential (Negri et al, 2012). The leaves of S. guianensis are the richest plant part in terms of essential oils.…”
Section: Introductionmentioning
confidence: 99%
“…The phytochemistry of the leaf crude extract suggests antimicrobial action, most likely because of the presence of terpenes, tannins and flavonoids (Bessa et al, 2013). Flavonoids of S. guianensis have anxiolytic potential and are indicated in complementary therapies to treat anxiety disorders and delay the aging process (Negri et al, 2012). There are also reports of the presence of flavonoids that may have anti-inflammatory action (Facundo et al, 2012).…”
Section: Introductionmentioning
confidence: 99%