Chemical composition and biological screening of Capsella bursa-pastoris

Abstract

Capsella bursa-pastoris (L.) Medik. (Brassicaceae) is a wild herb with high nutritional value that can be eaten raw or cooked. A metabolomic study was performed with different extracts of its aerial parts that were tested concerning their antiradical, acetylcholinesterase inhibitory and antibacterial activities. Phenolic compounds were identified and quantified by HPLC-DAD, organic acids and amino acids were determined by HPLC-UV, while free fatty acids and sterols were analysed by GC-ITMS. The vegetal material was rich in kaempferol-3-O-rutinoside (mean value 2247.09 mg/kg of dry plant), quinic acid (95628.00 mg/kg of dry plant), arginine (mean value of 1.18 mg/kg of dry plant), palmitic acid (284.48 mg/kg) and β-sitosterol (28%). The extracts presented a concentration-dependent antiradical activity (against DPPH• , O 2 •-and LOO • ), being most effective against • NO (EC25 0.20 μg/mL). In addition, the extracts were also acetylcholinesterase inhibitors and antibacterial active, revealing that, besides the plant's good nutritional value, it presents important biological properties as well.

ANTIFUNGAL POTENTIAL OF A BRASSICACEOUS WEED Sisymbrium irio AGAINST Macrophomina phaseolina

“…The phytochemical assessment of the weed has revealed that it is comprised of many secondary metabolites like flavonoids, alkaloids, oils, and glucosinolates (Khan et al, 1991;AlQudah and Abu Zarga, 2010;Shah et al, 2013). Previous literature has confirmed the antimicrobial activity of phenolic and flavonoid compounds of Brassicaeous plants (Mothana and Lindequist, 2005;Song et al, 2007;Grosso et al, 2011). However, S. irio has rarely been explored for its antifungal activity.…”

The Comparative Effect of Capsella bursa-pastoris and Mefenamic Acid on Sexual Function of Copper IUD Users

“…Therefore, this plant through reducing irregular period bleeding also leads to sexual functioning improvement. Bursa-pastoris like G. biloba contains flavonoids (18) and it seems that it plays an effective role, through similar mechanism, in the improvement of sexual functioning. Furthermore, due to having mineral materials, iron, magnesium, vitamins A, B and C, it can result in increment of sexual functioning like Max arginine supplement.…”

“…C. bursa-pastoris can be effective on smooth muscles of uterus and increase their contraction. Having hypochlorite effect, it is used orally for the treatment of uterus and severe bleedings (18,19). The hemostatic effects of this plant are exerted through several mechanisms including stimulation of uterus contractions, contraction of capillaries, stimulation of prothrombin production, and reduction of fragility in capillaries (20).…”

Synergistic Inhibition Effect Between Capsella bursa-pastoris Extracts and Iodide Ions for Q235 Mild Steel in 1 M HCl Solution

“…In the absence of iodide ions, the inhibitive action of CBE is due to the composition of numerous organic compounds [30][31][32] and may react with the ferrous ions, which result from the dissolution of steel (anodic reaction) [33], to form organometallic complex such as [Fe-CBE] to reduce hydrogen evolution reaction (cathodic reaction) according to the following mechanism [34]:…”

“…Its chemical composition, including minerals, vitamin A, ascorbic acid, proteins, linoleic acid and fatty acids, is considered to be beneficial to human health [10,11]. Besides the good nutritional value, Capsella bursa-pastoris presents important biological properties and medicinal properties, being used for antibleeding, anticancer [12], wound-healing and antioxidant agent [13], as well as for diabetes and fever treatment.…”