2012
DOI: 10.1590/s0102-695x2012005000018
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Chemical composition and anxiolytic-like effects of the Bauhinia platypetala

Abstract: Abstract:The pantropical genus Bauhinia, Fabaceae, known popularly as cow's foot, is widely used in folk medicine as antidiabetic. Behavioral effects of the ethanolic extract and ethereal, aqueous and ethyl acetate fractions from B. platypetala Benth. ex Hemsl. leaves were studied in male Swiss mice. The ethanolic extract and fractions were administered intraperitoneally and its effects on spontaneous motor activity (total motility, locomotion, rearing and grooming behavior) were monitored. Anxiolytic-like pro… Show more

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Cited by 8 publications
(3 citation statements)
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References 36 publications
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“…On the other hand, the forced or voluntary passages of animals into the closed arms of the EPM are associated with hormonal and behavioral changes indicative of increased anxiety (Hogg, 1996;Santos et al, 2012). Avoidance of the open arm portrays a manifestation of fear and anxiety.…”
Section: Discussionmentioning
confidence: 99%
“…On the other hand, the forced or voluntary passages of animals into the closed arms of the EPM are associated with hormonal and behavioral changes indicative of increased anxiety (Hogg, 1996;Santos et al, 2012). Avoidance of the open arm portrays a manifestation of fear and anxiety.…”
Section: Discussionmentioning
confidence: 99%
“…The arms perpendicularly intersect to form a cross, bounded by a central 10 × 10 cm area and 50 cm high from the ground. The maze is in a soundproof room, partially illuminated by an incandescent lamp (60 W), and is placed vertically, 150 cm above the apparatus [ 24 ].…”
Section: Methodsmentioning
confidence: 99%
“…forficata, B. purpurea, and B. platypetala, were also used to create various phototherapies (Melo, Nascimento, Amorim, Andrade Lima, & Albuquerque, 2004). These plants possess anxiolytic and antibacterial properties and have therefore been indicated for the treatment of diabetes (Albuquerque, Simira, & Silva, 2000;Ahmed et al, 2012;Santos et al, 2012;Pereira et al, 2014).…”
Section: Introductionmentioning
confidence: 99%