Chemical composition and antioxidant activity of a Lebanese plant Euphorbia macroclada schyzoceras

Farhan, Hussein; Rammal, Hassan; Hijazi, Akram; Daher, Ahmad; Reda, Mohamad; Annan, H.; Chokr, Ali; Bassal, Ali; Badran, Bassam

doi:10.1016/s2221-1691(13)60110-0

Cited by 23 publications

(15 citation statements)

References 16 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The value obtained in the present study was low when compared with the maximum chelating ability of hydroalcohol extract of Coriander sativum (90%) previously reported (Mirzae and Khatami, 2013). Our experimental value for chelating ability of D. stramonium extract in vitro state (70%) was the same to that of chelating ability of aqueous stem extract of Euphorbia macrolada (70%, at 1 mg/ml) reported by Farhan et al (2013). In the present study, the ethanolic root extract of D. stramonium showed concentration dependent decrease in chelating ability as the concentration of the extract increased, which was consistent with research work on chelating ability of Bauchinia purpurea stem bark extracts with ethyl acetate, petroleum ether and methanol as extraction solvents (Chaudhari and Nagar, 2013).…”

Section: Discussionsupporting

confidence: 85%

In vitro discovery of highly chelatable root extract of thorn apple (Datura stramonium)

Olabinri¹,

Fatunwase²,

Olabinri³

2014

Int. J. Med. Med. Sci.

View full text Add to dashboard Cite

This study investigated the in vitro chelating ability, antioxidant activity, total phenolic and flavonoid contents of 70% ethanolic extract of thorn apple (Datura stramonium). The ethanolic root extract of the plant displayed potent chelating ability (70%) at the lowest concentration (2%) investigated. The chelating ability of the extract showed concentration dependency. There were significant decreases in vitro chelating ability of the root extract from 2 to 10% concentrations (P<0.05). The root extract also demonstrated exhibited concentration dependent increases in antioxidant activity, which were nonsignificant from 2 to 6% concentrations (P>0.05) and significant from 8 to 10% (P<0.05). The ethanolic root extract displayed maximum activity [106.20±0.84% standard deviation (SD)] at the highest concentration (10%). The preliminary phytochemical screening of the aqueous extract of D. stramonium revealed the presence of flavonoids, tannin and alkaloid, but saponin was absent. The aqueous root extract of the plant also exhibited potent antioxidant potential (71.00%) at 2% concentration. The antioxidant activity of the aqueous root extract of the plant closely approximated the antioxidant activity of the ethanolic root extract of the plant (71.00 and 71.40%, at different concentrations, 2 and 5%, respectively). The aqueous root extract of the plant showed good in vitro nitric oxide radical scavenging activity (67.80%). The absolute and 70% acetone root extracts of the plant were dull nitric oxide scavengers (33.38 and 26.00%, respectively). The total flavonoid and phenolic contents of ethanolic root extract of D. stramonium showed non-significant increases as the concentration increased (P>0.05). The ethanolic root extract failed chelate ion at the highest concentration (10%) (-20.0% activity).

show abstract

Section: Discussionsupporting

confidence: 85%

In vitro discovery of highly chelatable root extract of thorn apple (Datura stramonium)

Olabinri¹,

Fatunwase²,

Olabinri³

2014

Int. J. Med. Med. Sci.

View full text Add to dashboard Cite

show abstract

“…Antioxidants can be defined as any compounds able to react with free radicals by neutralizing them to non-radical products and, consequently, these compounds can be used to stop or minimize the deleterious effects caused by free radicals in the human body [ 8 ]. Since the discovery of antioxidants, many types of analysis have been done to determine these substances, in terms of benefits and risks [ 9 ].…”

Section: Introductionmentioning

confidence: 99%

Phytochemical Investigation and Antioxidant Activity of Globularia alypum L.

et al. 2021

View full text Add to dashboard Cite

The Moroccan flora is rich in medicinal plants that are commonly used in folk medicine for the treatment of various diseases. The present study was designed to investigate the total phenolic and flavonoid contents, as well as the antioxidant properties of leaves extracts from Globularia alypum L. colected from the Taza region in northeast Morocco. Additionally, the individual phenolics and volatiles of the extracts were also evaluated. The organic extracts of this plant were obtained by Soxhlet extraction using two different solvents, namely ethyl acetate and chloroform. The antioxidant capacity of leaves extracts was measured using DPPH, ABTS and FRAP assays; the phenolic profile was determined by HPLC-DAD/ESI-MS analysis, whereas the volatile composition was elucidated by GC-MS. The ethyl acetate extract analysis showed a total of 20 phenolic compounds and the determination of phenolic contents showed a significant value of 56.5 ± 0.61 µg GAE/mg of extract in comparison with the chloroform extract (18.9 ± 0.48 µg GAE/mg of extract). Also, the determination of the flavonoid contents revealed that the ethyl acetate extract contained the highest value (30.2 ± 0.55 µg CE/mg of extract) in comparison with the chloroform extract (18.0 ± 0.36 µg CE/mg of extract). Concerning the antioxidant properties, interesting values were attained for the ethyl acetate extract which exhibited higher antioxidant activity, namely IC50 = 12.3 ± 3.83 µg/mL and IC50 = 37.0 ± 2.45 µg/mL for the DPPH and ABTS assays, respectively, whereas a value of 531.1 ± 17.08 (mg AAE/g DW) was obtained for the FRAP assay. Concerning the volatile profile, a total of 73 compounds were positively detected and among them n-hexadecanoic acid (13.5%) was the most abundant one. The results achieved confirm the important role of this plant as a source of natural antioxidants.

show abstract

“…Ethanolic extract showed higher antioxidant capacity than aqueous extract by using DPPH and H 2 O 2 tests, but with the using the chelating of ferrous ions test, the antioxidant activity of the aqueous extract of both stems and leaves was stronger than that of ethanolic once [159]. The leaves and stems of this plant have exerted high antioxidant power at different concentrations.…”

Section: Euphorbia Macrocladamentioning

confidence: 89%

Medicinal plants possessed antioxidant and free radical scavenging effects (part 3)- A review

Al-Snafi¹

2017

IOSRPHR

View full text Add to dashboard Cite

Abstract:-Antioxidants are substances that remove, prevent or delay oxidative damage to a target molecule. Therefore, an antioxidant may act to control the level of free radicals to counteract oxidative damage. The effects of medicinal plants in prevention and treatment of many diseases have been widely attributed to their antioxidants activities. This review was designed to highlight the antioxidant effects and free radical scavenging activity of medicinal plants as a third part of our previous reviews.

show abstract

Chemical composition and antioxidant activity of a Lebanese plant Euphorbia macroclada schyzoceras

Cited by 23 publications

References 16 publications

In vitro discovery of highly chelatable root extract of thorn apple (Datura stramonium)

In vitro discovery of highly chelatable root extract of thorn apple (Datura stramonium)

Phytochemical Investigation and Antioxidant Activity of Globularia alypum L.

Medicinal plants possessed antioxidant and free radical scavenging effects (part 3)- A review

Contact Info

Product

Resources

About