Chemical composition and antioxidant activity of essential oils of three endemic medicinal plants of Iran

Pirbalouti, Abdollah Ghasemi; Sedaghat, Leila; Hamedi, Behzad; Tirgir, Farhang

doi:10.3329/bjb.v42i2.18038

Cited by 16 publications

(9 citation statements)

References 20 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Although differences can be observed in the percentage distribution, in conformity with our findings (Z)-β-ocimene and α-pinene were dominant oil compounds in an earlier investigation. [32] Moreover, regarding the previously reported contents of the aerial parts, oil of the plant consists of monoterpenes as a major constituent [9] which is in conformity with our results. On the other hand, our findings differ from those reported in some investigations, in which other components such as α-phellandrene and β-phellandrene [3,9] , suberosin, spathulenol, trans-β-caryophyllene, arcurcumene, and bicyclogermacrene [6] , α-pinene, limonene, β-myrcene, and fenchyl acetate [9] were the major compounds.…”

Section: Oil Analysissupporting

confidence: 80%

“…[9,10,30] Chemical compounds and biological activity of some species from the genus Ferulago have been the subject of preceding studies. [8,9,14,17] The reports on the chemical compositions of the oils isolated from the aerial parts F. angulata are abundant [6,7,11,13,[30][31][32] as most of these investigations showed patterns of oil compositions similar to our present study. Although differences can be observed in the percentage distribution, in conformity with our findings (Z)-β-ocimene and α-pinene were dominant oil compounds in an earlier investigation.…”

Section: Oil Analysissupporting

confidence: 79%

See 1 more Smart Citation

Chemical composition, antibacterial and antifungal activities of seed essential oil of Ferulago angulata

Moghaddam

Mehdizadeh

Najafgholi

et al. 2018

International Journal of Food Properties

View full text Add to dashboard Cite

The aim of this study was to determine the chemical composition and the in vitro antimicrobial effects of seed essential oil of Ferulago angulata. The oil analyses by GC and GC/MS resulted in the identification of 39 compounds representing 91.07% of the oil. The major constituents were (Z)-β-ocimene (19.93%), α-pinene (15.50%), p-cymene (7.67%), sabinene (7.49%), β-phellandrene (5.5%), and α-phellandrene (4.95%). The oil was also screened for its antimicrobial properties against six bacteria (Erwinia amylovora, Xanthomonas oryzae, Pseudomonas syringae, Pectobacterium carotovorum, Ralstonia solanacearum, Bacillus thuringiensis) and six fungi (Alternaria alternata, Culvularia fallax, Macrophomina phaseolina, Fusarium oxysporum, Cytospora sacchari, Colletotrichum tricbellum). According to the results of antibacterial activity, B. thuringiensis (with 8 µL mL −1 minimal inhibitory concentration (MIC) and 15 µL mL −1 minimum bactericidal concentration (MBC)) was the most sensitive bacterium; P. carotovorum and R. solanacearum (with 20 µL mL −1 MIC and 30< MBC) were the most resistant bacteria. Additionally, a broad differentiation against all of the tested fungi showed that the most susceptible and resistant fungi after 6 days at the highest concentration (800 µL L −1 ) were F. oxysporum (100.0 ± 0.00%) and C. tricbellum (52.50 ± 1.67%) of growth inhibition, respectively. ARTICLE HISTORY

show abstract

Section: Oil Analysissupporting

confidence: 80%

Section: Oil Analysissupporting

confidence: 79%

Chemical composition, antibacterial and antifungal activities of seed essential oil of Ferulago angulata

Moghaddam

Mehdizadeh

Najafgholi

et al. 2018

International Journal of Food Properties

View full text Add to dashboard Cite

show abstract

“…F. angulata has already shown to have high antioxidant properties [14]. It has been reported that the hydroalcoholic extract of F. angulata can reduce serum levels of total cholesterol, triglycerides, and low-density lipoproteins (LDL) as well as inhibiting lipid peroxidation in Wistar rats [15].…”

Section: Introductionmentioning

confidence: 99%

Antiamnesic and Antioxidants Effects of Ferulago angulata Essential Oil Against Scopolamine-Induced Memory Impairment in Laboratory Rats

et al. 2015

View full text Add to dashboard Cite

Ferulago angulata (Apiaceae) is a shrub indigenous to western Iran, Turkey and Iraq. In traditional medicine, F. angulata is recommended for treating digestive pains, hemorrhoids, snake bite, ulcers and as sedative. In the present study, the effects of inhaled F. angulata essential oil (1 and 3%, daily, for 21 days) on spatial memory performance were assessed in scopolamine-treated rats. Scopolamine-induced memory impairments were observed, as measured by the Y-maze and radial arm-maze tasks. Decreased activities of superoxide dismutase, glutathione peroxidase and catalase along with increase of acetylcholinesterase activity and decrease of total content of reduced glutathione were observed in the rat hippocampal homogenates of scopolamine-treated animals as compared with control. Production of protein carbonyl and malondialdehyde significantly increased in the rat hippocampal homogenates of scopolamine-treated animals as compared with control, as a consequence of impaired antioxidant enzymes activities. Additionally, in scopolamine-treated rats exposure to F. angulata essential oil significantly improved memory formation and decreased oxidative stress, suggesting memory-enhancing and antioxidant effects. Therefore, our results suggest that multiple exposures to F. angulata essential oil ameliorate scopolamine-induced spatial memory impairment by attenuation of the oxidative stress in the rat hippocampus.

show abstract

“…The essential oils of F. sandrasica were also reported to have antibacterial and antioxidant activities with the emphasis that phenolic compounds may be responsible for the antioxidant activity . Moreover, F. angulata essential oil was determined to have antioxidant activities . In addition, it has been reported that Ferula assafoetida L. exhibited anxiolytic effects in rodents within the elevated plus‐maze model of anxiety .…”

Section: Introductionmentioning

confidence: 99%

Anxiolytic and antidepressant‐like effects of Ferulago angulata essential oil in the scopolamine rat model of Alzheimer's disease

Bağcı

Aydin

Mihășan

et al. 2015

Flavour & Fragrance J

View full text Add to dashboard Cite

Ferulago angulata subsp. carduchorum (Apiaceae) is a shrub indigenous to western Iran, Turkey and Iraq. In traditional medicine, F. angulata is recommended for treating digestive pains, haemorrhoids, snake bites, ulcers and as a sedative. The present study analysed the possible anxiolytic, antidepressant and antioxidant properties of F. angulata essential oil in a scopolamine‐induced rat model of Alzheimer's disease. The anxiolytic and antidepressant‐like effects of F. angulata essential oil were studied using in vivo (elevated plus‐maze and forced swimming tests) approaches. Also, the antioxidant activity in the amygdala was assessed using superoxide dismutase, glutathione peroxidase and catalase specific activities, the total content of the reduced glutathione, protein carbonyl and malondialdehyde levels. The scopolamine‐treated rats exhibited the following: a decrease in the percentage of the time spent and the number of entries in the open arm within the elevated plus‐maze test and a decrease of swimming time and an increase of immobility time in the forced swimming test. Inhalation of F. angulata essential oil significantly exhibited anxiolytic and antidepressant‐like effects and also antioxidant potential. Furthermore, in silico studies carried out by employing molecular docking experiments pointed to the existence of strong interactions of monoterpenes from F. angulata essential oil with anxiolytic and antidepressant effects with GABAA receptor. Our results suggest that the F. angulata essential oil inhalation ameliorates scopolamine‐induced anxiety and depression by attenuation of the oxidative stress in the rat amygdala. Copyright © 2015 John Wiley & Sons, Ltd.

show abstract

Chemical composition and antioxidant activity of essential oils of three endemic medicinal plants of Iran

Cited by 16 publications

References 20 publications

Chemical composition, antibacterial and antifungal activities of seed essential oil of Ferulago angulata

Chemical composition, antibacterial and antifungal activities of seed essential oil of Ferulago angulata

Antiamnesic and Antioxidants Effects of Ferulago angulata Essential Oil Against Scopolamine-Induced Memory Impairment in Laboratory Rats

Anxiolytic and antidepressant‐like effects of Ferulago angulata essential oil in the scopolamine rat model of Alzheimer's disease

Contact Info

Product

Resources

About