Chemical characterisation, hypoglycaemic and renoprotective effects of aqueous leaf extract of <i>Limoniastrum guyonianum</i> on fructose-induced metabolic syndrome in rats

Benkhaled, Abderrahim; Réggami, Yassine; Boudjelal, Amel; Senator, Abderrahmane; Bouriche, Hamama; Demirtaş, İbrahim; Kheniche, Abdelhakim; Benyettou, Halima; Larabi, Nadia; Ruberto, Giuseppe

doi:10.1080/13813455.2020.1739715

Cited by 5 publications

(2 citation statements)

References 47 publications

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“…Serum glucose level was quantified by using a reagent kit (Adaltis) according to the method described by Trinder (1969). Total cholesterol level and triglycerides (TG) were estimated (Aloud et al., 2018; Benkhaled et al., 2020) by using reagent kits (Chengxinde reagent company). HbA1c and liver enzymes (ALT and AST) were estimated and verified with kits (Ghaferi, Asadollahzadeh, et al, 2020; Lv et al., 2020) by using an HbA1c test kit (Beijing Wantai Dro Co., Ltd.) and AST and ALT commercial kits (Jiancheng Bioengineering Institute).…”

Section: Methodsmentioning

confidence: 99%

Camel milk as an alternative treatment regimen for diabetes therapy

Hussain

Wattoo

et al. 2021

Food Science & Nutrition

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Camel milk is a valuable source of nutrition with a wide range of therapeutic effects. Its unique composition helps to regulate the blood glucose level. The current study is aimed to evaluate the antidiabetic and hepatoprotective effects, as well as lipid profile restoration of camel milk in the diabetic mouse model. This innovative study evaluates the therapeutic effects of camel milk in diabetic mice by simultaneous measurement of blood glucose, HbA1c, ALT, AST, TG, cholesterol, and histopathological studies. The results showed that camel milk has significantly reduced blood glucose, HbA1c (p < .001), aspartate transaminase (AST), alanine transaminase (ALT) (p < .01), triglyceride (TG), and cholesterol (p < .01), compared to that in the diabetic control group. Also, the therapeutic effects of camel milk were completely comparable with the antidiabetic drug glibenclamide. The results of this study suggest that camel milk could be used as a proper alternative treatment regimen for diabetes therapy.

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Section: Methodsmentioning

confidence: 99%

Camel milk as an alternative treatment regimen for diabetes therapy

Hussain

Wattoo

et al. 2021

Food Science & Nutrition

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“…Upon evaluating the results of the studies, it becomes evident that herbs play a significant role in addressing various aspects of metabolic syndrome. A wide array of herbs have demonstrated the capacity to directly influence key metabolic parameters such as blood pressure, blood glucose levels, lipid profiles, obesity, and cholesterol and triglyceride levels ( Nikaein et al, 2016 ; Seong et al, 2021 ; Amin et al, 2015 ; Belcaro et al, 2013 ; Devaraj et al, 2013 ; Najmi et al, 2013 ; Mansouri et al, 2012 ; Shah et al, 2012 ; Basu et al, 2010 ; Gupta Jain et al, 2017 ; Mopuri et al, 2018 ; Cicolari et al, 2020 ; Chae et al, 2022 ; Dobhal et al, 2022 ; Jakovljevic et al, 2018 ; Reshidan et al, 2019 ; Verhoeven et al, 2015 ; Gurrola-Dlaz et al, 2010 ; Benkhaled et al, 2022 ; Li et al, 2020 ; Hermans et al, 2020 ; De Martin et al, 2018 ; Mayer et al, 2022 ; Kasabri et al, 2014 ; Tan et al, 2011 ; Kuate et al, 2015 ; Kho et al, 2016 ). However, while the breadth of herbs studied is extensive, evaluations reveal variations in their efficacy and mechanisms of action.…”

Section: Resultsmentioning

confidence: 99%

Natural products for managing metabolic syndrome: a scoping review

Abdulghani,

Al-Fayyadh

2024

Front. Pharmacol.

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IntroductionMetabolic syndrome comprises a collection of metabolic disorders stemming from factors like genetic predisposition, inadequate nutrition, stress, decreased physical activity, aging, and ethnicity. Although traditional pharmaceutical treatments exist for metabolic syndrome, their limited popularity is attributed to high costs and adverse effects. Consequently, natural products with fewer side effects have been explored for managing this condition. This literature review aims to explore the role of natural products including herbs, botanicals, vitamins, minerals, probiotics, and dietary supplements in managing metabolic syndrome.MethodsThis scoping review was conducted in five steps, involving the formulation of a research question, the retrieval and extraction of relevant studies, the selection of pertinent studies, the organization of information into tables, and the reporting of results. Data was collected from various databases including Embase, Science Direct, PubMed, Google Scholar, Scopus, and Web of Science, with a focus on studies published from 2010 to the present, available in English and with full-text accessibility.ResultsWe identified 1,259 articles, screened their titles, abstracts, and full texts, ultimately incorporating 169 pertinent articles into this review (comprising 90 review articles, 32 trial articles, 6 in vitro articles, 38 in vivo articles, 1 experimental article and 2 observational articles). The study’s outcomes revealed that natural products, encompassing plants and their derivatives, vitamins and supplements, as well as probiotics, can exert a beneficial influence on metabolic syndrome by regulating blood sugar, blood pressure, lipid profiles, obesity, and abnormal cholesterol and triglyceride levels.ConclusionThe current study underscores the significance of natural products in addressing metabolic syndrome. Consequently, it is advisable to conduct further extensive research to assess the efficacy of these products, potentially integrating them into treatment regimens for individuals with metabolic syndrome.

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