Chemical Biology: What is Its Role in Drug Discovery?

Pirrie, Lisa; Westwood, Nicholas J.

doi:10.5772/28599

Cited by 2 publications

(1 citation statement)

References 229 publications

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“…Following the drug's entry into the market, unceasing monitoring of its safety and efficacy, often involving pharmacovigilance and analytical methodologies, serves as the vanguard, ensuring the timely detection of adverse events. Analytical techniques are instrumental in the unmasking of counterfeit drugs, thereby acting as sentinels in the safeguarding of public health [6,7].…”

Section: Pharmaceutical Analysis In Drug Developmentmentioning

confidence: 99%

Pharmaceutical Analysis in Drug Discovery and Drug Development

Kosuru,

Rafi

et al. 2023

J Cli Pharm Res

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Pharmaceutical analysis stands as a linchpin within the intricate and multifaceted landscape of drug development. It assumes a pivotal role in upholding the safety, efficacy and quality of medicinal products at each juncture of their odyssey from conceptualization to market integration. Within this discourse, we delve into the paramount role of pharmaceutical analysis within the sphere of drug development. Pharmaceutical analysis plays an instrumental role in the identification and characterization of lead compounds that harbor therapeutic potential. Techniques such as high-throughput screening, mass spectrometry and nuclear magnetic resonance (NMR) serve as guiding lights in the quest for promising candidates. The elucidation of molecular structures through the means of NMR and X-ray crystallography takes center stage, facilitating a profound comprehension of the intricate interplay between drugs and biological targets. In this review we focused on role of pharmaceutical analysis in drug development and drug discovery. Inadequate pharmaceutical analysis and manufacturing practices can lead to the distribution of unsafe and ineffective medicines. Thus, adherence to cGMP is not only a legal obligation but also a moral imperative to protect public health and maintain the integrity of the pharmaceutical industry.

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Section: Pharmaceutical Analysis In Drug Developmentmentioning

confidence: 99%

Pharmaceutical Analysis in Drug Discovery and Drug Development

Kosuru,

Rafi

et al. 2023

J Cli Pharm Res

View full text Add to dashboard Cite

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Role of Pharmaceutical Sciences in Future Drug Discovery

Bonam

Sekar

Guntuku

et al. 2021

Future Drug. Discov.

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The recent emergence of COVID-19 influenced the layman’s knowledge of drugs. Although several drugs have been discovered serendipitously, research has moved to the next-generation era of drug discovery. The use of drugs is inevitable and they have become lifesavers in the present era. Although research from different scientific backgrounds has supported the translational research of drug discovery, the prime role of pharmacy has to be remembered. Here we have summarized the role of some important subjects in pharmacy education, which have paved different ways in drug discovery and development.

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Chemical Biology: What is Its Role in Drug Discovery?

Cited by 2 publications

References 229 publications

Pharmaceutical Analysis in Drug Discovery and Drug Development

Pharmaceutical Analysis in Drug Discovery and Drug Development

Role of Pharmaceutical Sciences in Future Drug Discovery

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