volume 9, issue 1, P124-136 2016
DOI: 10.15283/ijsc.2016.9.1.124
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Abstract: Background and ObjectivesAdipose-derived mesenchymal stem cells (ADSCs) are promising candidates in regenerative medicine. The need for in vitro propagation to obtain therapeutic quantities of the cells imposes a risk of impaired functionality due to cellular senescence. The aim of the study was to analyze in vitro senescence of previously cryopreserved human ADSCs subjected to serial passages in cell culture.Methods and ResultsADSC cultures from 8 donors were cultivated until proliferation arrest was reached.…

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