Characterization of Right Ventricular Diastolic Performance After Complete Repair of Tetralogy of Fallot

Cullen, Seamus; Shore, Darryl F.; Redington, Andrew N.

doi:10.1161/01.cir.91.6.1782

Cited by 260 publications

(181 citation statements)

References 14 publications

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“…Studies in the literature have shown that electrocardiographic, radiological, and clinical alterations may be related to the prognosis of the patient undergoing total repair of tetralogy of Fallot [1][2][3][4][5][6][7][8][9] . Biventricular systolic function is preserved in most patients [2][3][4] .…”

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confidence: 99%

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confidence: 99%

“…Biventricular systolic function is preserved in most patients [2][3][4] . However, right ventricular diastolic function has been recently observed to show signs of impairment with a diverse behavior in different phases of the postoperative follow-up [2][3][4] . This way, restrictive right ventricular physiology may be related to a complicated evolution in the early postoperative period [2][3][4]6 , but on the other hand, to a more favorable course in the late postoperative period 3 .…”

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confidence: 99%

“…However, right ventricular diastolic function has been recently observed to show signs of impairment with a diverse behavior in different phases of the postoperative follow-up [2][3][4] . This way, restrictive right ventricular physiology may be related to a complicated evolution in the early postoperative period [2][3][4]6 , but on the other hand, to a more favorable course in the late postoperative period 3 . This study aimed to assess the clinical, electrocardiographic, and radiological factors related to right ventricular diastolic dysfunction in the intermediate postoperative period of the repair of tetralogy of Fallot.…”

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confidence: 99%

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Right ventricular diastolic dysfunction in the postoperative period of tetralogy of Fallot

Cardoso¹,

Miyague²

2003

Arq. Bras. Cardiol.

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Right ventricular diastolic dysfunction in the postoperative period of tetralogy of Fallot

Cardoso¹,

Miyague²

2003

Arq. Bras. Cardiol.

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“…Three or more loops were stored for subsequent offline analysis. The presence of restrictive right ventricle physiology was defined as antegrade flow across the pulmonary artery coincident with atrial systole in all respiratory cycles [parasternal short axis right ventricle outflow tract view] (Cullen et al 1995).…”

Section: Perioperative Tissue Doppler Echocardiographymentioning

confidence: 99%

Heat shock protein 27 is increased in cyanotic tetralogy of Fallot myocardium and is associated with improved cardiac output and contraction

Walker¹,

Danton

Peng

et al. 2013

Cell Stress and Chaperones

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Tetralogy of Fallot (TOF) is a congenital heart condition in which the right ventricle is exposed to cyanosis and pressure overload. Patients have an increased risk of right ventricle dysfunction following corrective surgery. Whether the cyanotic myocardium is less tolerant of injury compared to non-cyanotic is unclear. Heat shock proteins (HSPs) protect against cellular stresses. The aim of this study was to examine HSP 27 expression in the right ventricle resected from TOF patients and determine its relationship with right ventricle function and clinical outcome. Ten cyanotic and ten noncyanotic patients were studied. Western blotting was used to quantify HSP 27 in resected myocardium at (1) baseline (first 15 min of aortic cross clamp and closest representation of preoperative status) and (2) after 15 min during ischemia until surgery was complete. The cyanotic group had significantly increased haematocrit, lower O 2 saturation, thicker interventricular septal wall thickness and released more troponin-I on post-operative day 1 (p<0.05). HSP 27 expression was significantly increased in the <15 min cyanotic compared to the <15 min non-cyanotic group (p00.03). In the cyanotic group, baseline HSP 27 expression also significantly correlated with oxygen extraction ratio (p00.028), post-operative basal septal velocity (p00.036) and mixed venous oxygen saturation (p00.02), markers of improved cardiac output/contraction. Increased HSP 27 expression and associated improved right ventricle function and systemic perfusion supports a cardioprotective effect of HSP 27 in cyanotic TOF.

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Cardiac Intensive Care

Jeremias¹,

Brown²

2005

Anesthesia for Congenital Heart Disease

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The specialty of pediatric cardiac critical care has undergone rapid scientific and clinical growth in the last 25 years. The Board of Directors of the Pediatric Cardiac Intensive Care Society assembled an updated list of sentinel references focused on the critical care of children with congenital and acquired heart disease. We encouraged board members to select articles that have influenced and informed their current practice or helped to establish the standard of care. The objective of this article is to provide clinicians with a compilation and brief summary of these updated 100 useful references. Data Sources: The list of "One Hundred Useful References for Pediatric Cardiac Intensive Care" ( 2004) and relevant literature to the practice of cardiac intensive care. Data Selection: A subset of Pediatric Cardiac Intensive Care Society board members compiled the initial list of useful references in 2004, which served as the basis of the new updated list. Suggestions for relevant articles were submitted by the Pediatric Cardiac Intensive Care Society board members and selected pediatric cardiac intensivists with an interest in this project following the Society's meeting in 2010. Articles were considered for inclusion if they were named in the original list from 2004 or were suggested by Pediatric Cardiac Intensive Care Society board members and published before December 31, 2011. Data Extraction: Following submission of the complete list by the Pediatric Cardiac Intensive Care Society board and contributing Society members, articles were complied by the two co-first authors (D.A., D.K.). The authors also performed Medline searches to ensure comprehensive inclusion of all relevant articles. The final list was then submitted to the Pediatric Cardiac Intensive Care Society board members, who ranked each publication. Data Synthesis: Rankings were compiled and the top 100 articles with the highest scores were selected for inclusion in this publication. The two co-first authors (D.A., D.K.) reviewed all existing summaries and developed summaries of the newly submitted articles.Conclusions: An updated compilation of 100 useful references for the critical care of children with congenital and acquired heart disease has been compiled and summarized here. Clinicians and trainees may wish to use this document as a reference for education in this complex and challenging subspecialty. (Pediatr Crit Care Med 2013; 14:770-785)

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Characterization of Right Ventricular Diastolic Performance After Complete Repair of Tetralogy of Fallot

Cited by 260 publications

References 14 publications

Right ventricular diastolic dysfunction in the postoperative period of tetralogy of Fallot

Right ventricular diastolic dysfunction in the postoperative period of tetralogy of Fallot

Heat shock protein 27 is increased in cyanotic tetralogy of Fallot myocardium and is associated with improved cardiac output and contraction

Cardiac Intensive Care

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